Tag Archives: transcriptomics

Systems Biology and Neurodegenerative Diseases

Neurodegenerative diseases (NDs) are complex disorders that affect more than 40 million people globally (Wood et al., 2015). The multifaceted variations in the pathophysiology of the diseases make it difficult for effective therapy or prevention of the disease progression. More … Continue reading

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Systems Biology and Drug Screening

Conventional drug design mostly uses the ligand and structure-based approaches (Prathipati and Mizuguchi, 2015). With the advancement in functional genomics and the availability of high-throughput (HTP) data, information on interactive molecular networks can be used to analyze the efficacy and … Continue reading

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Systems Biology, miRNAs, and Alzheimer’s Disease

Neurodegenerative diseases such as Alzheimer’s disease (AD) are multifactorial involving genomics, metabolomics, epigenomics, transcriptomics, interactomics, as well as environmental components. Systemic understanding of these complex diseases may start with the alterations in the cellular networks. Investigation in integrative systems biology … Continue reading

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Nutritional Systems Biology and Type 2 Diabetes

Systems biology studies include the investigations in various “omics” areas, such as genomics, transcriptomics, proteomics, metabolomics, epigenomics, as well as microbiomics. Combining both computational and experimental biology, systems biology aims at prediction of the dynamical processes and the description of … Continue reading

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The integration of various “omics” technologies in systems biology for better diagnosis and treatment

With the advancements in the “omics” technologies and the information technology, systems biology has become an important approach for biomarker discovery. These technologies allow faster and cheaper analyses of gene expression, protein interactions, signaling pathways, and metabolic mechanisms. In this … Continue reading

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