Tag Archives: Schizophrenia

Psychiatric Diseases and the Gene DISC1 (Disrupted in Schizophrenia 1)

The DISC1 gene has other symbols as “SCZD9” and “C1orf136”. It is located at 1q42.2. It is involved in the regulation of the AKT-mTOR signaling pathway and associated with embryonic and adult neurogenesis (Kim et al. 2009). DISC1 has been … Continue reading

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Stress, Depression, Inflammation, and Personalized Medicine

Stress, Depression, Inflammation, and Personalized Medicine Psychological stress has been associated with higher levels of inflammation and the risks of many physical disorders including heart diseases. For example, chronic stress responses may cause a variety of skin disorders including allergic … Continue reading

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PPARs, Psychoneuroimmunology, and Potential Treatment of Psychiatric Disorders

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of transcription factors that play important roles in glucose homeostasis, fatty acid and lipoprotein metabolism, and immune responses (Rolland et al., 2013). They are involved in the regulation of cellular proliferation and differentiation, … Continue reading

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Psychoneuroimmunology of Schizophrenia and Anti-Inflammatory Drugs

Studies in the psychoneuroimmunology of schizophrenia have revealed not only the neurological and cognitive alterations, but also the continuous systemic inflammation and neuroinflammation associated with microglia activation in the disease (Debnath and Venkatasubramanian, 2013). Activated peripheral and central inflammatory responses … Continue reading

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The Applications and Combination of Bioinformatics, Medical informatics, and Neuroinformatics

The Applications and Combination of Bioinformatics, Medical informatics, and Neuroinformatics   Mental disorders and other brain disorders such as anxiety, depression, schizophrenia, and visual impairments may account for at least one third of the worldwide burden of diseases (Wittchen et … Continue reading

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Neuroinformatics Databases for the Structure-Function Studies of the Brain

Neuroinformatics Databases for the Structure-Function Studies of the Brain     Category Source Name The Needs/Challenges Purposes/Features/Methods Contents Applications URL References Neuroinformatics Databases about the Brain Structures The Internet Brain Volume Database (IBVD) Available data from neuroanatomic volumetric measurements; Various … Continue reading

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Psychopathology: A Summary of Types, Disorders, and Concepts

Psychopathology: A Summary of Types, Disorders, and Concepts   Concepts/Theories/Sources Categories Categories Components/Disorders Problems Examples/Details Types/Examples Mental disorder features (Holmes) Distress Psychological discomfort         Disability Unable to do daily activities         Deviance Abnormal mood, … Continue reading

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