Tag Archives: psychiatric genetics

Alzheimer’s Disease and the Gene APOE (Apolipoprotein E)

The APOE gene has other symbols as “AD2”, “LPG”, “APO-E”, and “LDLCQ5”. It is located at 19q13.2. The APOE gene has important roles in cardiovascular diseases including myocardial infarction, ischemic stroke, and coronary heart disease (Kathiresan et al. 2008). The … Continue reading

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Psychiatric Symptoms and the Gene SGCE (Sarcoglycan Epsilon)

The SGCE gene has other symbols as “ESG” and “DYT11”. It is located at 7q21.3. As a member of the sarcoglycan family, it is a component of the dystrophin-glycoprotein complex (DGC). It provides the connections between the actin cytoskeleton and … Continue reading

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Epilepsy and the Gene KCNT1 (Potassium Sodium-Activated Channel Subfamily T member 1)

The KCNT1 gene has other symbols as “ENFL5”, “SLACK”, “EIEE14”, “KCa4.1”, “Slo2.2”, and “bA100C15.2”. It is located at 9q34.3. Encoding a sodium-activated potassium channel, this gene is highly expressed in the brain (Nagase et al. 2000). It has been related … Continue reading

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