Tag Archives: protein

The Database of Biomarkers: Depression: S100B

The potential biomarkers of depression: S100B Associated diseases: Burnout syndrome Population group: Emergency medicine residents Background: Burnout syndrome is a common issue among emergency healthcare workers. It may be related to fatigue and job separations. S100 calcium-binding protein B (S100B) … Continue reading

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Network Interactions, Interactomes, and Drug Discovery

Because genes and proteins are functioning in complex networks and interactions, one molecule may influence other cellular elements in a broad range. These interactions can be studied in “interactomes”, a term referring to the protein-protein interaction networks (Chautard et al., … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: Protein expressions   Potential Applications: “Predictive biomarkers for treatment response (to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram)”   … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum levels   Potential Applications: Predictive biomarkers (tumor progression and patient outcomes)   References: Shersher DD, Vercillo MS, Fhied C, Basu … Continue reading

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Neuroinformatics Databases about the Brain: Different Species

Neuroinformatics Databases about the Brain: Different Species   Species Source Name Purposes/Features/Methods Contents Applications URL References Mouse 3D digital atlas database of the mouse brain Lower spatial resolution images were utilized to enhance time efficiency for morphological phenotyping The in … Continue reading

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