Tag Archives: data

The Database of Biomarkers: Depression – fMRI Biomarkers

The Database of Biomarkers: Depression – fMRI Biomarkers •    Potential Biomarkers: Activation patterns: “greater and more sustained signals in three regions: BA24 (dorsal anterior cingulate), BA31 (posterior cingulate), and BA6 (prefrontal cortex)” Potential Applications: Diagnostic biomarkers in late-life anxious depression … Continue reading

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The Database of Biomarkers: Depression – EEG Biomarkers

The Database of Biomarkers: Depression – EEG Biomarkers •    Potential Biomarkers: “Midline and right frontal (MRF) cortical area,  early decreases in theta-band cordance” Potential Applications: Predictive biomarker of remission in major depressive disorder (MDD) References: Cook IA, Hunter AM, Abrams … Continue reading

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The Database of Biomarkers: Depression – Epigenetic Biomarkers

The Database of Biomarkers: Depression – Epigenetic Biomarkers •    Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters of the brain-derived neurotrophic factor (BDNF)” Potential Applications: Diagnostic biomarker References: Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki … Continue reading

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The Database of Biomarkers: Depression – MicroRNA Biomarkers

The Database of Biomarkers: Depression – MicroRNA Biomarkers •    Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for major depressive disorder (MDD) risks References: Xu Y, Liu H, Li F, Sun N, Ren Y, Liu Z, Cao X, … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers

The Database of Biomarkers: MicroRNA Biomarkers •    Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a (obesity); combination of miR-503 and miR-138 (diabetes) Potential Applications: Predictive biomarkers References: Pescador N, Pérez-Barba M, Ibarra JM, Corbatón A, … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders •    Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential Biomarkers: Brain-enriched plasma the “miR-132 family” (miR-128/miR-491-5p, miR-132/miR-491-5p and mir-874/miR-491-5p) and the “miR-134 family” (miR-134/miR-370, miR-323-3p/miR-370 and miR-382/miR-370) Potential Applications: … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: Protein expressions   Potential Applications: “Predictive biomarkers for treatment response (to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram)”   … Continue reading

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Neuroscience Data and Neuroinformatics

Neuroscience Data and Neuroinformatics   Neuroscience Data   At least 50% genes of the mammalian genome are expressed by the nervous system (Sutcliffe et al., 1991). To understand brain-related diseases, it is necessary to map and study the expression patterns … Continue reading

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Neuroinformatics Databases about the Brain: Different Species

Neuroinformatics Databases about the Brain: Different Species   Species Source Name Purposes/Features/Methods Contents Applications URL References Mouse 3D digital atlas database of the mouse brain Lower spatial resolution images were utilized to enhance time efficiency for morphological phenotyping The in … Continue reading

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Neuroinformatics Databases about the Brain-Related Diseases

Neuroinformatics Databases about the Brain-Related Diseases Disease Source Name Purposes/Features/Methods Contents Applications URL References Autism National Database for Autism Research (NDAR) A secure database for data sharing, data harmonization, and collaboration in autism spectrum disorder researchers Data from more than … Continue reading

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