Monthly Archives: April 2016
Challenges in Biomarker Discovery
Although biomarkers have been considered more and more important, it is still very difficult to identify and validate effective and useful biomarkers. The obstacles in the biomarker identification include both technical and theoretical reasons. For example, methods for identifying pathology-type … Continue reading
Biomarkers of Seasonal Allergic Rhinitis (SAR)
Seasonal allergic rhinitis (SAR) is not just a commonly seen health problem in certain seasons. It is also a risk factor that can lead to asthma among many people. Nasal allergies can promote bone-marrow eosinophil generation through cytokines such as … Continue reading
Systems Biology and Biomarkers in Neuropsychiatry
Neuropsychiatric (NP) disorders such as autism spectrum disorders (ASD) are the leading causes of disability around the world. However, because of their complexity, the etiology and pathophysiology of NP diseases are still mostly unknown. Such complexity may be caused by … Continue reading
Biomarkers, Oncology, and Precision Medicine
The identification of biomarkers is becoming more and more important in biomedicine, especially for the clinical practice. This is because biomarkers often contain valuable information about the pathology of the diseases such as cancers. Such information is useful for better … Continue reading
Systems Biology Technologies and Cancer Immunotherapy
Decades of scientific studies have demonstrated the essential role of the immune system in cancer pathology and clinical treatment. The immune system may regulate the growth of tumors via the complex interactions among molecules, genes, cells, and organs. The elucidation … Continue reading
Skin Disorders, Skinomics and Microarray Studies
The new field of “skinomics” refers to the use of systems biology and “omics” approaches in the studies of the skin and dermatology. For example, high-through put (HTP) methods such as microarrays have been applied to identify biomarkers including transcriptional … Continue reading
Systems Biomarkers and Skin Diseases
With the development of systems biology, bioinformatics, ‘omics’ studies, more and more discoveries are made in the disorders including cardiovascular diseases and cancer. However, although sometimes ignored, other common illnesses with high incidences including skin diseases also need more assessments … Continue reading
