• Associated diseases/conditions:

Breast cancer in the Mexican population

 

Potential Biomarkers:

Serum circulating miR-145, miR-155 and miR-382

 

Potential Applications:

Diagnostic biomarkers

 

References:

Mar-Aguilar F, Mendoza-Ramírez JA, Malagón-Santiago I, Espino-Silva PK, Santuario-Facio SK, Ruiz-Flores P, Rodríguez-Padilla C, Reséndez-Pérez D. Serum circulating microRNA profiling for identification of potential breast cancer biomarkers. Dis Markers. 2013;34(3):163-9. doi: 10.3233/DMA-120957. (http://www.ncbi.nlm.nih.gov/pubmed/23334650)

 

  • Associated diseases/conditions:

Stage III colorectal cancer (CRC)

 

Potential Biomarkers:

Serum circulating miR-18a and miR-29a

 

Potential Applications:

Screening and monitoring biomarkers

 

References:

Vega AB, Pericay C, Moya I, Ferrer A, Dotor E, Pisa A, Casalots À, Serra-Aracil X, Oliva JC, Ruiz A, Saigí E. microRNA expression profile in stage III colorectal cancer: circulating miR-18a and miR-29a as promising biomarkers. Oncol Rep. 2013 Jul;30(1):320-6. doi: 10.3892/or.2013.2475. (http://www.ncbi.nlm.nih.gov/pubmed/23673725)

 

  • Associated diseases/conditions:

Endometrioid endometrial cancer (EEC)

 

Potential Biomarkers:

Serum miR-222, miR-223, miR-186 and miR-204

 

Potential Applications:

Diagnostic biomarkers

 

References:

Jia W, Wu Y, Zhang Q, Gao G, Zhang C, Xiang Y. Identification of four serum microRNAs from a genome-wide serum microRNA expression profile as potential non-invasive biomarkers for endometrioid endometrial cancer. Oncol Lett. 2013 Jul;6(1):261-267. (http://www.ncbi.nlm.nih.gov/pubmed/23946815)

 

  • Associated diseases/conditions:

Classical Hodgkin Lymphoma (cHL)

 

Potential Biomarkers:

miR-494, miR-1973 and miR-21 (up-regulation)

 

Potential Applications:

Disease response biomarkers

 

References:

Jones KL, Nourse JP, Keane C, Bhatnagar A, Gandhi M. Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma. Clin Cancer Res. 2013  Nov 12. (http://www.ncbi.nlm.nih.gov/pubmed/24222179)


 

  • Associated diseases/conditions:

Early larynx carcinoma

 

Potential Biomarkers:

“30 up-regulated (e.g., hsa-miR-657), 17 down-regulated miRNA ( e.g., hsa-miR-1287)”

 

Potential Applications:

Predictive biomarkers for early diagnosis

 

References:

Wang Y, Chen M, Tao Z, Hua Q, Chen S, Xiao B. Identification of predictive biomarkers for early diagnosis of larynx carcinoma based on microRNA expression data. Cancer Genet. 2013 Oct 2. doi:pii: S2210-7762(13)00138-5. 10.1016/j.cancergen.2013.09.005. (http://www.ncbi.nlm.nih.gov/pubmed/24238754)

 

  • Associated diseases/conditions:

Lung cancer

 

Potential Biomarkers:

Plasma miR-205, -19a, -19b, -30b, and -20a

 

Potential Applications:

Diagnosis biomarkers

 

References:

Aushev VN, Zborovskaya IB, Laktionov KK, Girard N, Cros MP, Herceg Z, Krutovskikh V. Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma. PLoS One. 2013 Oct 9;8(10):e78649. doi: 10.1371/journal.pone.0078649. (http://www.ncbi.nlm.nih.gov/pubmed/24130905)

 

  • Associated diseases/conditions:

Non-small cell lung cancer (NSCLC)

 

Potential Biomarkers:

Serum miR-15b and miR-27b

 

Potential Applications:

Early diagnostic biomarkers

 

References:

Hennessey PT, Sanford T, Choudhary A, Mydlarz WW, Brown D, Adai AT, Ochs MF, Ahrendt SA, Mambo E, Califano JA. Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One. 2012;7(2):e32307. doi:10.1371/journal.pone.0032307. (http://www.ncbi.nlm.nih.gov/pubmed/22389695)

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