Tag Archives: psoriasis

Skin Disorders, Skinomics and Microarray Studies

The new field of “skinomics” refers to the use of systems biology and “omics” approaches in the studies of the skin and dermatology. For example, high-through put (HTP) methods such as microarrays have been applied to identify biomarkers including transcriptional … Continue reading

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Systems Biomarkers and Skin Diseases

With the development of systems biology, bioinformatics, ‘omics’ studies, more and more discoveries are made in the disorders including cardiovascular diseases and cancer. However, although sometimes ignored, other common illnesses with high incidences including skin diseases also need more assessments … Continue reading

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Psychoneuroimmunology, Stress Responses, and Chronic Inflammation

The interactions between the nervous and immune systems have been associated with psychosocial stress, peripheral inflammation, and chronic diseases (Liezmann et al., 2012; Peters et al., 2012). The concept of “inflammaging” refers to the premature aging with a pro-inflammatory condition … Continue reading

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PPARs, Psychoneuroimmunology, and Potential Treatment of Psychiatric Disorders

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of transcription factors that play important roles in glucose homeostasis, fatty acid and lipoprotein metabolism, and immune responses (Rolland et al., 2013). They are involved in the regulation of cellular proliferation and differentiation, … Continue reading

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Stress, Skin Disorders, and Psychoneuroimmunology

With a history of about 30 years, psychoneuroimmunology (PNI) studies the interactions among psychological activities, the nervous system, and the immune system. In the area of dermatology, many dermatologic diseases have been found to be related to mental and psychological … Continue reading

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