Tag Archives: polymorphism

Neuropsychiatric Disorders and the Gene COMT (Catechol-O-Methyltransferase)

The COMT gene has another symbol as “HEL-S-98n”. It is located at 22q11.21. It is an important enzyme in the process of metabolic degradation of catecholamines (Gogos et al., 1998). The 158met variant on the nondeleted allele has been related … Continue reading

Posted in Mind-Body, Psychiatric Genetics, Psychology, Psychoneuroimmunology | Tagged , , , , , , , , | Leave a comment

Anxiety and Polymorphisms in the Serotonin Transporter

Anxiety has been associated with transporter-assisted uptake of serotonin.  Many antidepressant and antianxiety drugs are selective serotonin reuptake inhibitors (SSRIs). Polymorphisms of the gene for the serotonin transporter (SERT, or SLC6A4) have been found to influence its functions and activities. … Continue reading

Posted in Psychoneuroimmunology | Tagged , , , , , , , , | Leave a comment