Tag Archives: neuropsychiatric

Cytokine Therapies and Psychiatric Disorders

Cytokine therapies including interferon-alpha (IF-alpha) and interleukin-2 (IL-2) have been used for cancers and chronic diseases including melanoma, hepatitis C, and multiple sclerosis. However, they may cause neuropsychiatric side effects (Myint et al., 2009). These side effects include depression, anxiety, … Continue reading

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Anxiety Disorders and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology The discoveries in psychoneuroimmunology (PNI) need to be translated into clinical care and better quality of life for patients. Such translational efforts are especially meaningful for the treatment of neuropsychiatric … Continue reading

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Neuropsychiatric Disorders and the Gene COMT (Catechol-O-Methyltransferase)

The COMT gene has another symbol as “HEL-S-98n”. It is located at 22q11.21. It is an important enzyme in the process of metabolic degradation of catecholamines (Gogos et al., 1998). The 158met variant on the nondeleted allele has been related … Continue reading

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Psychoneuroimmunology, Anxiety, and Inflammation

The emerging discipline of psychoneuroimmunology focuses on the interactions and cross talk among the immune system, the central nervous system (CNS), and behavior. For example, cytokines in the CNS have critical functions that can influence behavior. Such effects may result … Continue reading

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