Tag Archives: drug targets

Host Factors and Antiviral Targets

Host Factors and Antiviral Targets (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Host factors associated with SARS-CoV replication need to be investigated (de Wilde et al., 2015). These factors include the innate immune response and … Continue reading

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Antiviral Herbal Compounds for SARS-CoV Ion Channels

Antiviral Herbal Compounds for SARS-CoV Ion Channels (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) The protein coded by the open-reading-frame 3a of SARS coronavirus may form a cation-selective channel (Schwarz et al., 2014). The channel … Continue reading

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Systems Biology Approaches and Drug Design

The reductionist way of “one gene-one disease-one drug” has made it difficult for the discovery of more effective drugs.  In addition to conventional phenotypic and drug target screens, new methodologies may improve the drug design process, including ligand- and structure-based … Continue reading

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PPARs, Psychoneuroimmunology, and Potential Treatment of Psychiatric Disorders

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of transcription factors that play important roles in glucose homeostasis, fatty acid and lipoprotein metabolism, and immune responses (Rolland et al., 2013). They are involved in the regulation of cellular proliferation and differentiation, … Continue reading

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