Tag Archives: Database

Psychoneuroimmunology Database

The Database of Psychoneuroimmunology (DPNI) The Psychoneuroimmunology (PNI) Portal and Knowledge Base Potential Biomarkers for Anxiety The Database of Biomarkers: Depression Mind-Body Medicine About Meditation: The Portal and Knowledge Base The Nervous System Neuroinformatics The Database of Cytokines Chronobiology The … Continue reading

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Alzheimer’s Disease and the Gene APOE (Apolipoprotein E)

The APOE gene has other symbols as “AD2”, “LPG”, “APO-E”, and “LDLCQ5”. It is located at 19q13.2. The APOE gene has important roles in cardiovascular diseases including myocardial infarction, ischemic stroke, and coronary heart disease (Kathiresan et al. 2008). The … Continue reading

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The Database of Biological Rhythms (DBBR)

The Database of Biological Rhythms (DBBR) The Chronobiology Portal: Chronobiology, Chronotherapy, Circadian Rhythms, and More Journals about Biological Rhythms and Chronobiology   Biological Rhythm Research Chronobiology International Journal of Biological Rhythms Journal of Chronotherapy and Drug Delivery Journal of Circadian … Continue reading

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The Database of Biomarkers: Depression – fMRI Biomarkers

The Database of Biomarkers: Depression – fMRI Biomarkers •    Potential Biomarkers: Activation patterns: “greater and more sustained signals in three regions: BA24 (dorsal anterior cingulate), BA31 (posterior cingulate), and BA6 (prefrontal cortex)” Potential Applications: Diagnostic biomarkers in late-life anxious depression … Continue reading

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The Database of Biomarkers: Depression – EEG Biomarkers

The Database of Biomarkers: Depression – EEG Biomarkers •    Potential Biomarkers: “Midline and right frontal (MRF) cortical area,  early decreases in theta-band cordance” Potential Applications: Predictive biomarker of remission in major depressive disorder (MDD) References: Cook IA, Hunter AM, Abrams … Continue reading

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The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers •    Potential Biomarkers: The tryptophan-kynurenine pathway Detections: Increased indoleamine 2,3-dioxygenase activity Potential Applications: Diagnostic biomarkers References: Christmas DM, Potokar J, Davies SJ. A biological pathway linking inflammation and depression: activation … Continue reading

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The Database of Biomarkers: Depression – Epigenetic Biomarkers

The Database of Biomarkers: Depression – Epigenetic Biomarkers •    Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters of the brain-derived neurotrophic factor (BDNF)” Potential Applications: Diagnostic biomarker References: Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki … Continue reading

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The Database of Biomarkers: Depression – MicroRNA Biomarkers

The Database of Biomarkers: Depression – MicroRNA Biomarkers •    Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for major depressive disorder (MDD) risks References: Xu Y, Liu H, Li F, Sun N, Ren Y, Liu Z, Cao X, … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers

The Database of Biomarkers: MicroRNA Biomarkers •    Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a (obesity); combination of miR-503 and miR-138 (diabetes) Potential Applications: Predictive biomarkers References: Pescador N, Pérez-Barba M, Ibarra JM, Corbatón A, … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders •    Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential Biomarkers: Brain-enriched plasma the “miR-132 family” (miR-128/miR-491-5p, miR-132/miR-491-5p and mir-874/miR-491-5p) and the “miR-134 family” (miR-134/miR-370, miR-323-3p/miR-370 and miR-382/miR-370) Potential Applications: … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases •    Associated diseases/conditions: Atherosclerosis and stroke Potential Biomarkers: Serum miR-21 and miR-221 Potential Applications: Predictive biomarkers References: Tsai PC, Liao YC, Wang YS, Lin HF, Lin RT, Juo SH. Serum microRNA-21 … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers – Cancers

Associated diseases/conditions: Breast cancer in the Mexican population   Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382   Potential Applications: Diagnostic biomarkers   References: Mar-Aguilar F, Mendoza-Ramírez JA, Malagón-Santiago I, Espino-Silva PK, Santuario-Facio SK, Ruiz-Flores P, Rodríguez-Padilla C, Reséndez-Pérez D. … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: Protein expressions   Potential Applications: “Predictive biomarkers for treatment response (to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram)”   … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum levels   Potential Applications: Predictive biomarkers (tumor progression and patient outcomes)   References: Shersher DD, Vercillo MS, Fhied C, Basu … Continue reading

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Bioinformatics Databases and Tools for the Discovery of Proteomic and Pathway Biomarkers

BioLayout (http://www.biolayout.org/) Feature: “For the visualization and analysis of network graphs” Cytoscape (http://www.cytoscape.org/) Feature: “Network visualization” E-Cell (http://www.e-cell.org/) Feature: Computational models GelBank (http://gelbank.anl.gov/) Feature: “comparison of 2DE patterns in the context of proteome sequence queries” Gene Ontology (http://www.geneontology.org/) Feature: “Standardizing … Continue reading

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Bioinformatics Resources for MicroRNA (miRNA) Studies and Biomarker Discovery

CircuitsDB (http://biocluster.di.unito.it/circuits/) Feature: “MicroRNA / Transcription Factor Regulatory Circuits in Human and Mouse” deepBase (http://deepbase.sysu.edu.cn/) Feature: “For annotating and discovering small and long ncRNAs” Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo/) Feature: “The miRNA expression profile” HOCTARdb (http://hoctar.tigem.it/) Feature: “microRNA target prediction” … Continue reading

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Neuroinformatics Databases about the Brain: Different Species

Neuroinformatics Databases about the Brain: Different Species   Species Source Name Purposes/Features/Methods Contents Applications URL References Mouse 3D digital atlas database of the mouse brain Lower spatial resolution images were utilized to enhance time efficiency for morphological phenotyping The in … Continue reading

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Neuroinformatics Databases about the Brain-Related Diseases

Neuroinformatics Databases about the Brain-Related Diseases Disease Source Name Purposes/Features/Methods Contents Applications URL References Autism National Database for Autism Research (NDAR) A secure database for data sharing, data harmonization, and collaboration in autism spectrum disorder researchers Data from more than … Continue reading

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Neuroinformatics Databases about the Brain Structures

Neuroinformatics Databases about the Brain Structures   The Internet Brain Volume Database (IBVD) (Kennedy et al., 2012) The URL: http://www.nitrc.org/projects/ibvd The background Publications available about Neuroanatomic volumetric observations Large data sets of volumetric measurements with variables of Specific species Structures … Continue reading

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