Tag Archives: cytokines

Cytokines, Depression, and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Cytokines such as interferon (IFN)-alpha may cause dopamine depletion and affect the pathways of monoamine metabolism. Their alterations may result in behavioral changes including depression, psychomotor slowing, and fatigue (Miller, … Continue reading

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Stress, Immunity, and Breast Cancer Patients

Breast cancer patients after surgery often have higher levels of distress and need psychosocial adaptation to the new conditions. The problems of distress among these patients have been related to cellular immune dysfunctions with the negative impacts on the recovery … Continue reading

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Anxiety Disorders and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology The discoveries in psychoneuroimmunology (PNI) need to be translated into clinical care and better quality of life for patients. Such translational efforts are especially meaningful for the treatment of neuropsychiatric … Continue reading

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Anxiety, Depression, and Seasonal Allergic Rhinitis (SAR)

Increasing evidences have indicated the strong connections between seasonal allergic rhinitis (SAR) and psychological conditions, especially anxiety and depression. A recent study done in Germany explored the roles of anxiety and depression in the patients with SAR (Trikojat et al. … Continue reading

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Chronobiology, Chronotherapy, and Rheumatoid Arthritis

Chronobiology studies biological cycles or rhythms. Circadian rhythms are critical for the maintenance of cellular and psychophysiological health. Many health problems are affected by the time of day. For example, the symptoms of rheumatoid arthritis (RA) including joint pain and … Continue reading

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Circadian Rhythms and Stem Cell Chronobiology

Circadian rhythms are biological temporal patterns that oscillate in a 24-hour time cycle. Many physiological processes and behavioral variations are controlled by the rhythms, such as the daily sleep-waking cycle. The secretions of hormones and cytokines such as melatonin and … Continue reading

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Psychoneuroimmunology, Anxiety, and Inflammation

The emerging discipline of psychoneuroimmunology focuses on the interactions and cross talk among the immune system, the central nervous system (CNS), and behavior. For example, cytokines in the CNS have critical functions that can influence behavior. Such effects may result … Continue reading

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Stress, Depression, and Inflammation

Inflammation is a risk factor for many aging problems such as metabolic syndrome, Type 2 diabetes, cardiovascular disease, and frailty (Jaremka et al., 2013). Inflammation can be enhanced by stress and depression, such as in the condition of troubled relationships. … Continue reading

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Autism Spectrum Disorders (ASD), Cytokines, and Immune Functions

Autism spectrum disorders (ASD) has been associated with the malfunctions of multiple biological systems and pathways, especially the cytokines of the immune system. The altered immune functions may influence crucial neurodevelopmental processes (Napolioni et al., 2013). For example, the cytokines … Continue reading

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Cytomegalovirus (CMV) Infections, Psychological Stress, and Mood Disorders

Cytomegalovirus (CMV) is a beta-herpes virus that may be associated with aging and many health problems. The infection of CMV can be asymptomatic. However, higher levels of serum cytokines including TNF-alpha and IL-6 have been observed in CMV infections, which … Continue reading

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Stress, Skin Disorders, and Psychoneuroimmunology

With a history of about 30 years, psychoneuroimmunology (PNI) studies the interactions among psychological activities, the nervous system, and the immune system. In the area of dermatology, many dermatologic diseases have been found to be related to mental and psychological … Continue reading

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The Integration of Immunology and Neuroscience

Although immunology and neuroscience are seemingly two different and separate disciplines, recent findings have blurred the boundaries between them. For example, a cytokine that was previously clearly defined in the immune system, interleukin-1 (IL-1), has been found to have the … Continue reading

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The Database of Cytokine Receptors: L – P

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions LIFR SWS; SJS2; STWS; CD118; LIF-R; FLJ98106; FLJ99923 LEUKEMIA INHIBITORY FACTOR RECEPTOR   NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser … Continue reading

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The Database of Cytokine Receptors: I

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IFNAR1 AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC INTERFERON, ALPHA, BETA, AND OMEGA, RECEPTOR 1 IFNAR ANTIVIRAL PROTEIN, ALPHA TYPE; AVP ANTIVIRAL PROTEIN, BETA TYPE … Continue reading

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The Database of Cytokine Receptors: C

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions CCR2   chemokine (C-C motif) receptor 2 CKR2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2 NCBI Gene Map Viewer HPRD SNP: Genotype … Continue reading

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The Cytokine Database: T – X

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions TNFRSF11B OPG; TR1; OCIF; MGC29565 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 11B NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser     … Continue reading

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The Cytokine Database: O – S

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways OSM MGC20461 ONCOSTATIN M NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics Association DB GWAS Central HGVS MutaDATABASE SNP SNP: … Continue reading

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The Cytokine Database: M – N

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions MDK MK; NEGF2; FLJ27379 MIDKINE NCBI GeneOMIM EnsemblNCBI Map Viewer UCSC Genome Browser UniProtHPRD Genetics Association DBGWAS Central HGVS MutaDATABASE SNP SNP: GeneView KEGG … Continue reading

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The Cytokine Database: ISG – L

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways ISG15 G1P2; IP17; UCRP; IFI15; hUCRP UBIQUITIN-LIKE MODIFIER ISG15 NCBI GeneOMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics Association DBGWAS CentralHGVS MutaDATABASE … Continue reading

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The Cytokine Database: Interleukins

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IL1A IL1; IL-1A; IL1F1; IL1-ALPHA INTERLEUKIN 1-ALPHA NCBI GeneOMIM Ensembl NCBI Map ViewerUCSC Genome Browser UniProt HPRD Genetics Association DBGWAS CentralHGVSMutaDATABASE SNP SNP: GeneView … Continue reading

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The Cytokine Database: Interferons

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IFNA1 IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; MGC138207; MGC138505; MGC138507; IFN-alphaD INTERFERON, ALPHA-1 NCBI GeneOMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics … Continue reading

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The Cytokine Database: D – F

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions DMKN UNQ729; ZD52F10; FLJ79374 Dermokine 93099 Genome ProteinHPRD SNPSNP: GeneView KEGG EBI3 IL27B; IL-27B EPSTEIN-BARR VIRUS-INDUCED GENE 3 NCBI GeneOMIM Ensembl NCBI Map ViewerUCSC … Continue reading

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The Cytokine Database: A – C

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions AIMP1 p43; HLD3; EMAP2; SCYE1; EMAPII AMINOACYL-tRNA SYNTHETASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 NCBI GeneOMIM EnsemblNCBI Map ViewerUCSC Genome Browser UniProtHPRD     Genetics Association … Continue reading

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