Tag Archives: Cancer

Anxiety, Sleep, Fatigue, Inflammation, and Advanced Cancer

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Patients with terminal cancer are often troubled with fatigue (Rodrigues et al., 2016). Studies on the mechanisms would be helpful for improving the quality of life of the patients. A … Continue reading

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Meditation, Life Style Changes, and Cancer Treatment

Meditation can benefit the recovery from chronic diseases as it helps one make lifestyle changes and deal with pain and stress. It helps detach our emotions from the illness and boost our immune system. It can improve food digestion, blood … Continue reading

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Meditation, Cognition, and Cancer Therapies

Cognitive impairment is often related with cancer, and may limit the quality of life in cancer patients and survivors. Abnormal neurologic structure and function have been reported in cancer patients. Researchers at University of Texas MD Anderson Cancer Center studied … Continue reading

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The Interactions between Natural Killer Cells and Monocytes in Anti-Cancer Therapies

Human natural killer (NK) cells, monocytes, and dendritic cells are important components of the innate immune functions with instant protections against cancer cells and infections. Monocytes are large white blood cells (also called leukocytes). They can become macrophages and obtain … Continue reading

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Inflammation and Diseases

Inflammation is an immune response of the body to protect from irritants, stimuli, or external materials that may be detrimental. Inflammatory signs: Redness Swelling Heat Pain Immune surveillance: The immune system can monitor, find, and remove the useless or damaging … Continue reading

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Systems Biology Technologies and Cancer Immunotherapy

Decades of scientific studies have demonstrated the essential role of the immune system in cancer pathology and clinical treatment. The immune system may regulate the growth of tumors via the complex interactions among molecules, genes, cells, and organs. The elucidation … Continue reading

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Stress, Depression, Inflammation, and Personalized Medicine

Stress, Depression, Inflammation, and Personalized Medicine Psychological stress has been associated with higher levels of inflammation and the risks of many physical disorders including heart diseases. For example, chronic stress responses may cause a variety of skin disorders including allergic … Continue reading

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Systems Biology, Immunity, Biomarkers, and Aging

Many chronic diseases are age-associated, including Alzheimer’s disease, cardiovascular disease, type 2 diabetes, and cancer. The elevating incidence of these disorders asks for the better understanding of the associations between the aging process and various diseases. With the increasing life … Continue reading

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Stress, Chronic Diseases, and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Although many chronic diseases such as cancer are apparently physical, they can lead to psychological distress. Chronic psychosocial stress may in turn affect the physical health negatively. Studies in psychoneuroimmunology (PNI) have shown that the … Continue reading

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The Database of Biological Rhythms (DBBR)

The Database of Biological Rhythms (DBBR) The Chronobiology Portal: Chronobiology, Chronotherapy, Circadian Rhythms, and More Journals about Biological Rhythms and Chronobiology   Biological Rhythm Research Chronobiology International Journal of Biological Rhythms Journal of Chronotherapy and Drug Delivery Journal of Circadian … Continue reading

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Circadian Rhythms and Stem Cell Chronobiology

Circadian rhythms are biological temporal patterns that oscillate in a 24-hour time cycle. Many physiological processes and behavioral variations are controlled by the rhythms, such as the daily sleep-waking cycle. The secretions of hormones and cytokines such as melatonin and … Continue reading

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Mind-Body Methods May Improve Sleep Quality in Cancer Patients

Cancer patients often have sleep problems that influence their quality of life and disease recovery. Mind-body interventions (MBIs) are known to improve sleep quality. It is necessary to find out if MBIs are also beneficial for improving the sleep quality … Continue reading

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Stress Screening and Mind-Body Medicine for Chronic Diseases

Although many chronic and severe diseases such as cancer are apparently physical, they can also lead to psychological distress and poor quality of life. On the other hand, chronic stress may affect the physical biological systems negatively and cause unfavorable … Continue reading

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PPARs, Psychoneuroimmunology, and Potential Treatment of Psychiatric Disorders

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of transcription factors that play important roles in glucose homeostasis, fatty acid and lipoprotein metabolism, and immune responses (Rolland et al., 2013). They are involved in the regulation of cellular proliferation and differentiation, … Continue reading

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The Associations between Depression and Chronic Diseases

Depression is becoming a leading cause of disability with loss of work days globally. It is also one of the most important risk factors in many chronic diseases. Depression plays a critical role in the etiology, progression, and results of … Continue reading

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Behavioral Problems in Cancer Patients and Survivors: Factors in Psychoneuroimmunology

Behavioral symptoms are commonly seen in cancer patients and survivors. For example, in breast cancer patients, such symptoms include depression, cognitive impairment, sleep disorders, and fatigue (Bower, 2008). These symptoms have adverse effects on the treatment results of cancers. They … Continue reading

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Effects of Psychosocial Therapies for Cancer Patients: Psychoneuroimmunology (PNI)-Based Analysis

Cancer patients often have psychological problems too, such as stress and depression. It is critical to address the psychosocial demands of cancer patients. On the basis of the scientific studies of psychoneuroimmunology (PNI), methods in psychosocial therapies have been applied … Continue reading

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Childhood Trauma, Life Stress, and Risk Factors for Chronic Fatigue

Chronic fatigue syndrome (CFS) is a common health problem, especially in cancer survivors. To provide better care and prevention for patients with fatigue, it is important to understand the risk factors for this health problem. Studies have linked childhood stress … Continue reading

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The Database of Biomarkers: MicroRNA Biomarkers – Cancers

Associated diseases/conditions: Breast cancer in the Mexican population   Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382   Potential Applications: Diagnostic biomarkers   References: Mar-Aguilar F, Mendoza-Ramírez JA, Malagón-Santiago I, Espino-Silva PK, Santuario-Facio SK, Ruiz-Flores P, Rodríguez-Padilla C, Reséndez-Pérez D. … Continue reading

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The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum levels   Potential Applications: Predictive biomarkers (tumor progression and patient outcomes)   References: Shersher DD, Vercillo MS, Fhied C, Basu … Continue reading

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Systems biology and “omics” technologies for better drug discovery and outcome studies in cancer treatment

The multiple platforms using the “omics” technologies and the integration of systems biology approaches including both experimental and computational methods would support both drug target discovery and clinical outcome studies, especially in cancer treatment. For instance, immunotherapies have become an … Continue reading

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Individualized systems medicine (ISM): applications in the treatment of acute myeloid leukemia (AML)

Approaches in individualized systems medicine (ISM) or personalized systems medicine would be useful for achieving optimal therapies, especially in cancer treatment. Strategies in ISM have been suggested by Pemovska et al., by focusing on the establishment of molecular profiling (Pemovska … Continue reading

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Psychosocial Factors and Cancer Progression: Psychoneuroimmunology (PNI) Mechanisms

Psychosocial factors have been found to play important roles in the development of various diseases, including cancer progression. Such associations are mediated via the biobehavioral pathways in various patient populations, including the hematopoietic stem cell transplant (HCT) patients (Knight et … Continue reading

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