Tag Archives: biomarkers

Biomarkers Database: Obesity in Different Populations

Park, B.-Y., Hong, J., & Park, H. (2017). Neuroimaging biomarkers to associate obesity and negative emotions. Scientific Reports, 7(1), 7664. https://doi.org/10.1038/s41598-017-08272-8 Pecht, T., Gutman-Tirosh, A., Bashan, N., & Rudich, A. (2014). Peripheral blood leucocyte subclasses as potential biomarkers of adipose … Continue reading

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Biomarkers Database: Obesity, Cognition, and Inflammation

Garcia-Mazcorro, J. F., Mills, D. A., Murphy, K., & Noratto, G. (2018). Effect of barley supplementation on the fecal microbiota, caecal biochemistry, and key biomarkers of obesity and inflammation in obese db/db mice. European Journal of Nutrition, 57(7), 2513–2528. https://doi.org/10.1007/s00394-017-1523-y … Continue reading

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Biomarkers Database: Obesity, Metabolic Disorders, and Cardiovascular Risks

Aleksandrova, K., Mozaffarian, D., & Pischon, T. (2018). Addressing the Perfect Storm: Biomarkers in Obesity and Pathophysiology of Cardiometabolic Risk. Clinical Chemistry, 64(1), 142–153. https://doi.org/10.1373/clinchem.2017.275172 Bagheri, M., Djazayery, A., Qi, L., Yekaninejad, M. S., Chamari, M., Naderi, M., … Farzadfar, … Continue reading

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Potential Biomarkers of Obesity

For obesity with cardiovascular diseases: Peterson, S. J., Shapiro, J. I., Thompson, E., Singh, S., Liu, L., Weingarten, J. A., … Abraham, N. G. (2019). Oxidized HDL, Adipokines, and Endothelial Dysfunction: A Potential Biomarker Profile for Cardiovascular Risk in Women … Continue reading

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Anxiety, Depression, and Inflammation: Physical and Cognitive Aspects

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology More and more evidences have related anxiety and depression to elevated systemic inflammation (Duivis et al., 2013). As complex disorders, anxiety and depression have heterogeneity in symptoms with both physical … Continue reading

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Anxiety, Inflammation, and Patient Groups

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Similar to depression, anxiety disorders have also been related to metabolic and cardiovascular disorders. Does inflammation provide the connection between anxiety and these physical disorders? What are the possible relationships … Continue reading

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Fear, Anxiety, PTSD, GAD, and Inflammation

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Fear- and anxiety-associated problems have been related to inflammation. As evidences, pro-inflammatory biomarkers have been found to be associated with affective behaviors (Michopoulos et al., 2017). For example, in mental … Continue reading

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Anxiety, Sleep, Fatigue, Inflammation, and Advanced Cancer

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Patients with terminal cancer are often troubled with fatigue (Rodrigues et al., 2016). Studies on the mechanisms would be helpful for improving the quality of life of the patients. A … Continue reading

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Anxiety, Inflammation, and Obesity

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Anxiety and depression have been related to the higher levels of inflammation among those with obesity. This group of people may also have the higher risks of cardiovascular disease (CVD) … Continue reading

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Anxiety and Inflammation in Breast Cancer Survivors

Breast cancer survivors often have continuous psychological disorders such as anxiety and depression. Such mood problems may be caused by stress, and affect the quality of life (Pyter et al., 2017). Neuroinflammation may have a critical role in the mood … Continue reading

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Obesity, Emotional Conditions, Eating Behaviors, and Inflammation

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Obesity has been associated with chronic low-degree inflammation that can result in stress and behavioral problems. A study investigated the correlations among adiposity, low-grade inflammation, eating behaviors, and emotional conditions … Continue reading

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Anxiety Disorders and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology The discoveries in psychoneuroimmunology (PNI) need to be translated into clinical care and better quality of life for patients. Such translational efforts are especially meaningful for the treatment of neuropsychiatric … Continue reading

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Stress and Inflammatory Biomarkers in Psychiatric Disorders among Children and Adolescents

Inflammation, immune dysfunctions, and abnormal cytokine levels have been closely related to psychiatric disorders among adult patients in recent studies in psychoneuroimmunology (PNI). How about the associations between cytokine concentrations and psychosocial stress in children and adolescents (C&A)? A recent … Continue reading

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Potential Biomarkers for Anxiety

•    Potential Biomarker: Serum levels of lipid hydroperoxide (LOOH) •    Type:    Serum •    Relevance: The serum levels of lipid hydroperoxide have been considered as a potential biomarker for anxiety disorders among children (Ceylan et al., 2014). •    Potential Biomarker: Nighttime … Continue reading

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Effects of Mind-Body Interventions on the Proinflammatory Transcription Factor NF-κB

Mind-body interventions such as Tai Chi, Qigong, yoga, and meditation have been found to improve the quality of life. Recent studies have shown that these methods may affect the biological activities especially inflammation. A meta-study of 26 trials about mind-body … Continue reading

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The Database of Biomarkers: Depression: S100B

The potential biomarkers of depression: S100B Associated diseases: Burnout syndrome Population group: Emergency medicine residents Background: Burnout syndrome is a common issue among emergency healthcare workers. It may be related to fatigue and job separations. S100 calcium-binding protein B (S100B) … Continue reading

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The Database of Biomarkers: Depression: Adiponectin

The potential biomarkers of depression: Adiponectin Associated diseases: Chronic hepatitis C Population group: Patients with hepatitis C virus (HCV) infections Background: Major depression (MD) is often observed among patients with hepatitis C virus (HCV) infections. These patients treated with interferon … Continue reading

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Translational Medicine and Drug Discovery

Recent development in translational medicine provides a connection between basic scientific studies and clinical practice. Such an initiative may support the patient-centered objectives in both research and clinical environments. It may also improve the drug discovery procedure by allowing for … Continue reading

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Genetic Networks and Biomarkers

The post-genomic research based on large cohorts of preclinical studies have produced multi-dimensional genetic and transcriptomic data sets. The revelation of the molecular pathways and cellular networks associated with various diseases may promote the systems biology studies of the onset … Continue reading

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Systems Biology and Companion Diagnostics

The development in high-throughput (HTP) technologies and computational biology may help define the next generation of biomarkers. By providing an integrative viewpoint, systems biology may improve the understanding of the complexity in biological systems. The assemblage of interacting molecular elements … Continue reading

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Challenges in Biomarker Discovery

Although biomarkers have been considered more and more important, it is still very difficult to identify and validate effective and useful biomarkers. The obstacles in the biomarker identification include both technical and theoretical reasons. For example, methods for identifying pathology-type … Continue reading

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Biomarkers of Seasonal Allergic Rhinitis (SAR)

Seasonal allergic rhinitis (SAR) is not just a commonly seen health problem in certain seasons. It is also a risk factor that can lead to asthma among many people. Nasal allergies can promote bone-marrow eosinophil generation through cytokines such as … Continue reading

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Systems Biology and Biomarkers in Neuropsychiatry

Neuropsychiatric (NP) disorders such as autism spectrum disorders (ASD) are the leading causes of disability around the world. However, because of their complexity, the etiology and pathophysiology of NP diseases are still mostly unknown. Such complexity may be caused by … Continue reading

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Biomarkers, Oncology, and Precision Medicine

The identification of biomarkers is becoming more and more important in biomedicine, especially for the clinical practice. This is because biomarkers often contain valuable information about the pathology of the diseases such as cancers. Such information is useful for better … Continue reading

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Systems Biology Technologies and Cancer Immunotherapy

Decades of scientific studies have demonstrated the essential role of the immune system in cancer pathology and clinical treatment. The immune system may regulate the growth of tumors via the complex interactions among molecules, genes, cells, and organs. The elucidation … Continue reading

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