Tag Archives: biomarker
Biomarkers Database: Obesity in Different Populations
Park, B.-Y., Hong, J., & Park, H. (2017). Neuroimaging biomarkers to associate obesity and negative emotions. Scientific Reports, 7(1), 7664. https://doi.org/10.1038/s41598-017-08272-8 Pecht, T., Gutman-Tirosh, A., Bashan, N., & Rudich, A. (2014). Peripheral blood leucocyte subclasses as potential biomarkers of adipose … Continue reading
Biomarkers Database: Obesity, Cognition, and Inflammation
Garcia-Mazcorro, J. F., Mills, D. A., Murphy, K., & Noratto, G. (2018). Effect of barley supplementation on the fecal microbiota, caecal biochemistry, and key biomarkers of obesity and inflammation in obese db/db mice. European Journal of Nutrition, 57(7), 2513–2528. https://doi.org/10.1007/s00394-017-1523-y … Continue reading
The Effects of Medical Qigong on Quality of Life in Cancer Patients
Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology How to Practice Qigong: The Basics and Principles In cancer patients, quality of life (QOL) of is often reduced because of the side effects of anticancer treatments. Medical Qigong is … Continue reading
The Database of Biomarkers: Depression: S100B
The potential biomarkers of depression: S100B Associated diseases: Burnout syndrome Population group: Emergency medicine residents Background: Burnout syndrome is a common issue among emergency healthcare workers. It may be related to fatigue and job separations. S100 calcium-binding protein B (S100B) … Continue reading
Genetic Networks and Biomarkers
The post-genomic research based on large cohorts of preclinical studies have produced multi-dimensional genetic and transcriptomic data sets. The revelation of the molecular pathways and cellular networks associated with various diseases may promote the systems biology studies of the onset … Continue reading
Systems Biology and Companion Diagnostics
The development in high-throughput (HTP) technologies and computational biology may help define the next generation of biomarkers. By providing an integrative viewpoint, systems biology may improve the understanding of the complexity in biological systems. The assemblage of interacting molecular elements … Continue reading
Biomarkers for Inflammatory Breast Cancer
Inflammatory breast cancer (IBC) is an aggressive type of breast cancers (BC). Currently only a few specific genetic biomarkers or signatures have been identified for the disease. However, these genetic signatures are not very representative (Remo et al. 2015). More … Continue reading
Systems Biology, Lipidomics, and Cardiovascular Disease
Atherosclerosis involves a gradual process of inflammation with the stiffening of the arterial wall. This inflammatory condition can be caused by many factors, including elevated cellularity, lipid accrual, cellular debris, as well as extracellular substances (De Leon et al., 2015). … Continue reading
The Database of Biomarkers: Depression – fMRI Biomarkers
The Database of Biomarkers: Depression – fMRI Biomarkers • Potential Biomarkers: Activation patterns: “greater and more sustained signals in three regions: BA24 (dorsal anterior cingulate), BA31 (posterior cingulate), and BA6 (prefrontal cortex)” Potential Applications: Diagnostic biomarkers in late-life anxious depression … Continue reading
The Database of Biomarkers: Depression – EEG Biomarkers
The Database of Biomarkers: Depression – EEG Biomarkers • Potential Biomarkers: “Midline and right frontal (MRF) cortical area, early decreases in theta-band cordance” Potential Applications: Predictive biomarker of remission in major depressive disorder (MDD) References: Cook IA, Hunter AM, Abrams … Continue reading
The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers
The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers • Potential Biomarkers: The tryptophan-kynurenine pathway Detections: Increased indoleamine 2,3-dioxygenase activity Potential Applications: Diagnostic biomarkers References: Christmas DM, Potokar J, Davies SJ. A biological pathway linking inflammation and depression: activation … Continue reading
The Database of Biomarkers: Depression – Epigenetic Biomarkers
The Database of Biomarkers: Depression – Epigenetic Biomarkers • Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters of the brain-derived neurotrophic factor (BDNF)” Potential Applications: Diagnostic biomarker References: Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki … Continue reading
The Database of Biomarkers: Depression – MicroRNA Biomarkers
The Database of Biomarkers: Depression – MicroRNA Biomarkers • Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for major depressive disorder (MDD) risks References: Xu Y, Liu H, Li F, Sun N, Ren Y, Liu Z, Cao X, … Continue reading
The Database of Biomarkers: MicroRNA Biomarkers
The Database of Biomarkers: MicroRNA Biomarkers • Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a (obesity); combination of miR-503 and miR-138 (diabetes) Potential Applications: Predictive biomarkers References: Pescador N, Pérez-Barba M, Ibarra JM, Corbatón A, … Continue reading
The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders
The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders • Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential Biomarkers: Brain-enriched plasma the “miR-132 family” (miR-128/miR-491-5p, miR-132/miR-491-5p and mir-874/miR-491-5p) and the “miR-134 family” (miR-134/miR-370, miR-323-3p/miR-370 and miR-382/miR-370) Potential Applications: … Continue reading
The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases
The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases • Associated diseases/conditions: Atherosclerosis and stroke Potential Biomarkers: Serum miR-21 and miR-221 Potential Applications: Predictive biomarkers References: Tsai PC, Liao YC, Wang YS, Lin HF, Lin RT, Juo SH. Serum microRNA-21 … Continue reading
The Database of Biomarkers: MicroRNA Biomarkers – Cancers
Associated diseases/conditions: Breast cancer in the Mexican population Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382 Potential Applications: Diagnostic biomarkers References: Mar-Aguilar F, Mendoza-Ramírez JA, Malagón-Santiago I, Espino-Silva PK, Santuario-Facio SK, Ruiz-Flores P, Rodríguez-Padilla C, Reséndez-Pérez D. … Continue reading
The Database of Biomarkers: Proteomic and Pathway Biomarkers
Associated diseases/conditions: Depression Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway” Detections: Protein expressions Potential Applications: “Predictive biomarkers for treatment response (to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram)” … Continue reading
Bioinformatics Databases and Tools for the Discovery of Proteomic and Pathway Biomarkers
BioLayout (http://www.biolayout.org/) Feature: “For the visualization and analysis of network graphs” Cytoscape (http://www.cytoscape.org/) Feature: “Network visualization” E-Cell (http://www.e-cell.org/) Feature: Computational models GelBank (http://gelbank.anl.gov/) Feature: “comparison of 2DE patterns in the context of proteome sequence queries” Gene Ontology (http://www.geneontology.org/) Feature: “Standardizing … Continue reading
