Tag Archives: biomarker

Biomarkers Database: Obesity in Different Populations

Posted on May 25, 2019 by Pharm Tao

Park, B.-Y., Hong, J., & Park, H. (2017). Neuroimaging biomarkers to associate obesity and negative emotions. Scientific Reports, 7(1), 7664. https://doi.org/10.1038/s41598-017-08272-8 Pecht, T., Gutman-Tirosh, A., Bashan, N., & Rudich, A. (2014). Peripheral blood leucocyte subclasses as potential biomarkers of adipose … Continue reading →

Posted in Bioinformatics, Biomarkers, Obesity | Tagged , , , , , , , , | Leave a comment

Biomarkers Database: Obesity, Cognition, and Inflammation

Posted on May 23, 2019 by Pharm Tao

Garcia-Mazcorro, J. F., Mills, D. A., Murphy, K., & Noratto, G. (2018). Effect of barley supplementation on the fecal microbiota, caecal biochemistry, and key biomarkers of obesity and inflammation in obese db/db mice. European Journal of Nutrition, 57(7), 2513–2528. https://doi.org/10.1007/s00394-017-1523-y … Continue reading →

Posted in Bioinformatics, Biomarkers, Obesity | Tagged , , , , , , , | Leave a comment

Biomarkers Database: Obesity, Metabolic Disorders, and Cardiovascular Risks

Posted on May 21, 2019 by Pharm Tao

Aleksandrova, K., Mozaffarian, D., & Pischon, T. (2018). Addressing the Perfect Storm: Biomarkers in Obesity and Pathophysiology of Cardiometabolic Risk. Clinical Chemistry, 64(1), 142–153. https://doi.org/10.1373/clinchem.2017.275172 Bagheri, M., Djazayery, A., Qi, L., Yekaninejad, M. S., Chamari, M., Naderi, M., … Farzadfar, … Continue reading →

Posted in Bioinformatics, Biomarkers, Obesity | Tagged , , , , , , , , , | Leave a comment

The Effects of Medical Qigong on Quality of Life in Cancer Patients

Posted on September 22, 2017 by Pharm Tao

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology How to Practice Qigong: The Basics and Principles In cancer patients, quality of life (QOL) of is often reduced because of the side effects of anticancer treatments. Medical Qigong is … Continue reading →

Posted in Meditation, Mind-Body, Psychoneuroimmunology | Tagged , , , , , , | Leave a comment

The Database of Biomarkers: Depression: S100B

Posted on August 8, 2016 by Pharm Tao

The potential biomarkers of depression: S100B Associated diseases: Burnout syndrome Population group: Emergency medicine residents Background: Burnout syndrome is a common issue among emergency healthcare workers. It may be related to fatigue and job separations. S100 calcium-binding protein B (S100B) … Continue reading →

Posted in Biomarkers, Mind-Body | Tagged , , , , , , , , , , | Leave a comment

Genetic Networks and Biomarkers

Posted on May 15, 2016 by Pharm Tao

The post-genomic research based on large cohorts of preclinical studies have produced multi-dimensional genetic and transcriptomic data sets. The revelation of the molecular pathways and cellular networks associated with various diseases may promote the systems biology studies of the onset … Continue reading →

Posted in Systems Biology | Tagged , , , , , , , , | Leave a comment

Systems Biology and Companion Diagnostics

Posted on May 11, 2016 by Pharm Tao

The development in high-throughput (HTP) technologies and computational biology may help define the next generation of biomarkers. By providing an integrative viewpoint, systems biology may improve the understanding of the complexity in biological systems. The assemblage of interacting molecular elements … Continue reading →

Posted in Systems Biology | Tagged , , , , , , , , , | Leave a comment

Biomarkers for Inflammatory Breast Cancer

Posted on May 8, 2016 by Pharm Tao

Inflammatory breast cancer (IBC) is an aggressive type of breast cancers (BC). Currently only a few specific genetic biomarkers or signatures have been identified for the disease. However, these genetic signatures are not very representative (Remo et al. 2015). More … Continue reading →

Posted in Systems Biology | Tagged , , , , , , , , , | Leave a comment

Systems Biology, Lipidomics, and Cardiovascular Disease

Posted on October 24, 2015 by Pharm Tao

Atherosclerosis involves a gradual process of inflammation with the stiffening of the arterial wall. This inflammatory condition can be caused by many factors, including elevated cellularity, lipid accrual, cellular debris, as well as extracellular substances (De Leon et al., 2015). … Continue reading →

Posted in Systems Biology | Tagged , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Depression – fMRI Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: Depression – fMRI Biomarkers •    Potential Biomarkers: Activation patterns: “greater and more sustained signals in three regions: BA24 (dorsal anterior cingulate), BA31 (posterior cingulate), and BA6 (prefrontal cortex)” Potential Applications: Diagnostic biomarkers in late-life anxious depression … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Depression – EEG Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: Depression – EEG Biomarkers •    Potential Biomarkers: “Midline and right frontal (MRF) cortical area,  early decreases in theta-band cordance” Potential Applications: Predictive biomarker of remission in major depressive disorder (MDD) References: Cook IA, Hunter AM, Abrams … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers •    Potential Biomarkers: The tryptophan-kynurenine pathway Detections: Increased indoleamine 2,3-dioxygenase activity Potential Applications: Diagnostic biomarkers References: Christmas DM, Potokar J, Davies SJ. A biological pathway linking inflammation and depression: activation … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Depression – Epigenetic Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: Depression – Epigenetic Biomarkers •    Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters of the brain-derived neurotrophic factor (BDNF)” Potential Applications: Diagnostic biomarker References: Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Depression – MicroRNA Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: Depression – MicroRNA Biomarkers •    Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for major depressive disorder (MDD) risks References: Xu Y, Liu H, Li F, Sun N, Ren Y, Liu Z, Cao X, … Continue reading →

Posted in Bioinformatics, Biomarkers, MicroRNA | Tagged , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: MicroRNA Biomarkers

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: MicroRNA Biomarkers •    Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a (obesity); combination of miR-503 and miR-138 (diabetes) Potential Applications: Predictive biomarkers References: Pescador N, Pérez-Barba M, Ibarra JM, Corbatón A, … Continue reading →

Posted in Bioinformatics, Biomarkers, MicroRNA | Tagged , , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders •    Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential Biomarkers: Brain-enriched plasma the “miR-132 family” (miR-128/miR-491-5p, miR-132/miR-491-5p and mir-874/miR-491-5p) and the “miR-134 family” (miR-134/miR-370, miR-323-3p/miR-370 and miR-382/miR-370) Potential Applications: … Continue reading →

Posted in Bioinformatics, Biomarkers, MicroRNA | Tagged , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases

Posted on December 9, 2013 by Pharm Tao

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases •    Associated diseases/conditions: Atherosclerosis and stroke Potential Biomarkers: Serum miR-21 and miR-221 Potential Applications: Predictive biomarkers References: Tsai PC, Liao YC, Wang YS, Lin HF, Lin RT, Juo SH. Serum microRNA-21 … Continue reading →

Posted in Bioinformatics, Biomarkers, MicroRNA | Tagged , , , , , , , , , , | Leave a comment

The Database of Biomarkers: MicroRNA Biomarkers – Cancers

Posted on December 9, 2013 by Pharm Tao

Associated diseases/conditions: Breast cancer in the Mexican population   Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382   Potential Applications: Diagnostic biomarkers   References: Mar-Aguilar F, Mendoza-Ramírez JA, Malagón-Santiago I, Espino-Silva PK, Santuario-Facio SK, Ruiz-Flores P, Rodríguez-Padilla C, Reséndez-Pérez D. … Continue reading →

Posted in Bioinformatics, Biomarkers, MicroRNA | Tagged , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Proteomic and Pathway Biomarkers

Posted on December 9, 2013 by Pharm Tao

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: Protein expressions   Potential Applications: “Predictive biomarkers for treatment response (to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram)”   … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , | Leave a comment

The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

Posted on December 9, 2013 by Pharm Tao

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum levels   Potential Applications: Predictive biomarkers (tumor progression and patient outcomes)   References: Shersher DD, Vercillo MS, Fhied C, Basu … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , | Leave a comment

Bioinformatics Databases and Tools for the Discovery of Proteomic and Pathway Biomarkers

Posted on December 8, 2013 by Pharm Tao

BioLayout (http://www.biolayout.org/) Feature: “For the visualization and analysis of network graphs” Cytoscape (http://www.cytoscape.org/) Feature: “Network visualization” E-Cell (http://www.e-cell.org/) Feature: Computational models GelBank (http://gelbank.anl.gov/) Feature: “comparison of 2DE patterns in the context of proteome sequence queries” Gene Ontology (http://www.geneontology.org/) Feature: “Standardizing … Continue reading →

Posted in Bioinformatics, Biomarkers, Systems Biology | Tagged , , , , , , , , , , , , | Leave a comment