Rheumatoid Arthritis, Fibromyalgia Syndrome, and Sleep Quality

Patients with rheumatoid arthritis (RA) and fibromyalgia syndrome (FMS) often have poor sleep quality (Ulus et al., 2012; Nicassio et al., 2014). For example, in a study of 107 patients, rheumatoid arthritis (RA) was found to be associated with the sleep quality factor but not the sleep efficiency factor (Nicassio et al., 2014).

In another study of patients with rheumatoid arthritis and fibromyalgia syndrome, patients had more significant depression, higher pain and fatigue scores than those of the control subjects (Ulus et al., 2012). These patients also had poor sleep quality. In addition, compared with RA patients, FMS patients had worse sleep efficiency with daytime dysfunction.

These studies have indicated that sleep quality may be influenced by depression, fatigue, pain, and other disease activities in patients with rheumatoid arthritis and fibromyalgia syndrome. Further studies are still needed to find out how to improve sleep quality and efficiency in these patients.


Nicassio PM, Ormseth SR, Custodio MK, Olmstead R, Weisman MH, Irwin MR. Confirmatory factor analysis of the Pittsburgh Sleep Quality Index in rheumatoid arthritis patients. Behav Sleep Med. 2014;12(1):1-12. doi: 10.1080/15402002.2012.720315.

Ulus Y, Akyol Y, Tander B, Durmus D, Bilgici A, Kuru O. Sleep quality in fibromyalgia and rheumatoid arthritis: associations with pain, fatigue, depression, and disease activity. Clin Exp Rheumatol. 2011 Nov-Dec;29(6 Suppl 69):S92-6.

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