Ovarian cancer and distress are often seen together. To promote the therapeutic effects and quality of life for the patients, the factors involved in the associations between psychological distress and ovarian cancer need to be found (Arden-Close et al., 2008).
In a meta-analysis of 18 relevant studies, some correlations were found between psychological changes (including anxiety and depression) with the factors of younger age, as well as disease stages and symptoms (Arden-Close et al., 2008). Other factors may include the immune functions.
These studies have demonstrated that among the patient group of ovarian cancer, psychological stress has been related to the demographic factors and disease symptoms (Arden-Close et al., 2008). More studies in psychoneuroimmunology (PNI) would be needed to understand the psychological and immunological interactions in the associated disorders.
Arden-Close E, Gidron Y, Moss-Morris R. Psychological distress and its correlates in ovarian cancer: a systematic review. Psychooncology. 2008 Nov;17(11):1061-72. doi: 10.1002/pon.1363.