The Database of Biomarkers: Depression: Adiponectin

July 27, 2016
Biomarkers

The potential biomarkers of depression: Adiponectin Associated diseases: Chronic hepatitis C Population group: Patients with hepatitis C virus (HCV) infections …Read the Rest

Translational Medicine and Drug Discovery

May 25, 2016
Systems Biology

Recent development in translational medicine provides a connection between basic scientific studies and clinical practice. Such an initiative may support …Read the Rest

Systems Biology Approaches and Drug Design

May 19, 2016
Systems Biology

The reductionist way of “one gene-one disease-one drug” has made it difficult for the discovery of more effective drugs.  In …Read the Rest

Genetic Networks and Biomarkers

May 15, 2016
Systems Biology

The post-genomic research based on large cohorts of preclinical studies have produced multi-dimensional genetic and transcriptomic data sets. The revelation …Read the Rest

Systems Biology and Companion Diagnostics

May 11, 2016
Systems Biology

The development in high-throughput (HTP) technologies and computational biology may help define the next generation of biomarkers. By providing an …Read the Rest

Biomarkers for Inflammatory Breast Cancer

May 8, 2016
Systems Biology

Inflammatory breast cancer (IBC) is an aggressive type of breast cancers (BC). Currently only a few specific genetic biomarkers or …Read the Rest

Challenges in Biomarker Discovery

April 29, 2016
Biomarkers

Although biomarkers have been considered more and more important, it is still very difficult to identify and validate effective and …Read the Rest

Biomarkers of Seasonal Allergic Rhinitis (SAR)

April 26, 2016
Biomarkers

Seasonal allergic rhinitis (SAR) is not just a commonly seen health problem in certain seasons. It is also a risk …Read the Rest

Systems Biology and Biomarkers in Neuropsychiatry

April 22, 2016
Biomarkers

Neuropsychiatric (NP) disorders such as autism spectrum disorders (ASD) are the leading causes of disability around the world. However, because …Read the Rest

Biomarkers, Oncology, and Precision Medicine

April 21, 2016
Biomarkers

The identification of biomarkers is becoming more and more important in biomedicine, especially for the clinical practice. This is because …Read the Rest

Systems Biology Technologies and Cancer Immunotherapy

April 19, 2016
Systems Biology

Decades of scientific studies have demonstrated the essential role of the immune system in cancer pathology and clinical treatment. The …Read the Rest

Skin Disorders, Skinomics and Microarray Studies

April 16, 2016
Systems Biology

The new field of “skinomics” refers to the use of systems biology and “omics” approaches in the studies of the …Read the Rest

Systems Biomarkers and Skin Diseases

April 12, 2016
Systems Biology

With the development of systems biology, bioinformatics, ‘omics’ studies, more and more discoveries are made in the disorders including cardiovascular …Read the Rest

Alzheimer’s Disease and the Gene APOE (Apolipoprotein E)

March 8, 2016
Mind-Body

The APOE gene has other symbols as “AD2”, “LPG”, “APO-E”, and “LDLCQ5”. It is located at 19q13.2. The APOE gene …Read the Rest

Psychiatric Symptoms and the Gene SGCE (Sarcoglycan Epsilon)

March 1, 2016
Mind-Body

The SGCE gene has other symbols as “ESG” and “DYT11”. It is located at 7q21.3. As a member of the …Read the Rest

Epilepsy and the Gene KCNT1 (Potassium Sodium-Activated Channel Subfamily T member 1)

February 25, 2016
Brain

The KCNT1 gene has other symbols as “ENFL5”, “SLACK”, “EIEE14”, “KCa4.1”, “Slo2.2”, and “bA100C15.2”. It is located at 9q34.3. Encoding …Read the Rest

Neuropsychiatric Disorders and the Gene COMT (Catechol-O-Methyltransferase)

February 23, 2016
Mind-Body

The COMT gene has another symbol as “HEL-S-98n”. It is located at 22q11.21. It is an important enzyme in the …Read the Rest

Psychiatric Diseases and the Gene DISC1 (Disrupted in Schizophrenia 1)

February 20, 2016
Mind-Body

The DISC1 gene has other symbols as “SCZD9” and “C1orf136”. It is located at 1q42.2. It is involved in the …Read the Rest

Stress, Depression, Inflammation, and Personalized Medicine

February 19, 2016
Mind-Body

Stress, Depression, Inflammation, and Personalized Medicine Psychological stress has been associated with higher levels of inflammation and the risks of …Read the Rest

Systems Biology, Immunity, Biomarkers, and Aging

January 8, 2016
Systems Biology

Many chronic diseases are age-associated, including Alzheimer’s disease, cardiovascular disease, type 2 diabetes, and cancer. The elevating incidence of these …Read the Rest

Systems Biology, Lipidomics, and Cardiovascular Disease

October 24, 2015
Systems Biology

Atherosclerosis involves a gradual process of inflammation with the stiffening of the arterial wall. This inflammatory condition can be caused …Read the Rest

Network Interactions, Interactomes, and Drug Discovery

October 18, 2015
Systems Biology

Because genes and proteins are functioning in complex networks and interactions, one molecule may influence other cellular elements in a …Read the Rest

Stress, Chronic Diseases, and Psychoneuroimmunology

October 10, 2015
Psychiatric Genetics

Stress, Chronic Diseases, and Psychoneuroimmunology Although many chronic diseases such as cancer are apparently physical, they can lead to psychological …Read the Rest

Systems Biology and Neurodegenerative Diseases

September 30, 2015
Psychiatric Genetics

Neurodegenerative diseases (NDs) are complex disorders that affect more than 40 million people globally (Wood et al., 2015). The multifaceted …Read the Rest

Systems Biology and Drug Screening

September 17, 2015
Systems Biology

Conventional drug design mostly uses the ligand and structure-based approaches (Prathipati and Mizuguchi, 2015). With the advancement in functional genomics …Read the Rest

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Mind-Body, Personalized, and Systems Medicine