Systems Medicine

Translational Medicine and Drug Discovery

May 25, 2016
Systems Biology

Recent development in translational medicine provides a connection between basic scientific studies and clinical practice. Such an initiative may support …Read the Rest

Challenges in Biomarker Discovery

April 29, 2016
Biomarkers

Although biomarkers have been considered more and more important, it is still very difficult to identify and validate effective and …Read the Rest

Biomarkers of Seasonal Allergic Rhinitis (SAR)

April 26, 2016
Biomarkers

Seasonal allergic rhinitis (SAR) is not just a commonly seen health problem in certain seasons. It is also a risk …Read the Rest

Systems Biology and Biomarkers in Neuropsychiatry

April 22, 2016
Biomarkers

Neuropsychiatric (NP) disorders such as autism spectrum disorders (ASD) are the leading causes of disability around the world. However, because …Read the Rest

Biomarkers, Oncology, and Precision Medicine

April 21, 2016
Biomarkers

The identification of biomarkers is becoming more and more important in biomedicine, especially for the clinical practice. This is because …Read the Rest

Cytomegalovirus (CMV) Infections, Psychological Stress, and Mood Disorders

March 4, 2014
Infectious Diseases

Cytomegalovirus (CMV) is a beta-herpes virus that may be associated with aging and many health problems. The infection of CMV …Read the Rest

Stress, Skin Disorders, and Psychoneuroimmunology

February 28, 2014
Psychoneuroimmunology

With a history of about 30 years, psychoneuroimmunology (PNI) studies the interactions among psychological activities, the nervous system, and the …Read the Rest

The Database of Biomarkers: Depression – fMRI Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – fMRI Biomarkers •    Potential Biomarkers: Activation patterns: “greater and more sustained signals in three …Read the Rest

The Database of Biomarkers: Depression – EEG Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – EEG Biomarkers •    Potential Biomarkers: “Midline and right frontal (MRF) cortical area,  early decreases …Read the Rest

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers •    Potential Biomarkers: The tryptophan-kynurenine pathway Detections: Increased indoleamine 2,3-dioxygenase …Read the Rest

The Database of Biomarkers: Depression – Epigenetic Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – Epigenetic Biomarkers •    Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters …Read the Rest

The Database of Biomarkers: Depression – MicroRNA Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – MicroRNA Biomarkers •    Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers •    Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders •    Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases •    Associated diseases/conditions: Atherosclerosis and stroke Potential Biomarkers: Serum miR-21 and …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Cancers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Breast cancer in the Mexican population   Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382   Potential Applications: …Read the Rest

The Database of Biomarkers: Proteomic and Pathway Biomarkers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: …Read the Rest

The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum …Read the Rest

Bioinformatics Databases and Tools for the Discovery of Proteomic and Pathway Biomarkers

December 8, 2013
Bioinformatics

BioLayout (http://www.biolayout.org/) Feature: “For the visualization and analysis of network graphs” Cytoscape (http://www.cytoscape.org/) Feature: “Network visualization” E-Cell (http://www.e-cell.org/) Feature: Computational …Read the Rest

Bioinformatics Resources for MicroRNA (miRNA) Studies and Biomarker Discovery

December 7, 2013
Bioinformatics

CircuitsDB (http://biocluster.di.unito.it/circuits/) Feature: “MicroRNA / Transcription Factor Regulatory Circuits in Human and Mouse” deepBase (http://deepbase.sysu.edu.cn/) Feature: “For annotating and discovering …Read the Rest

Journals Focusing on Biomarkers

November 24, 2013
Biomarkers

Biomarker Insights Biomarker Research Biomarkers Biomarkers and Genomic Medicine Biomarkers in Cancer Biomarkers in Medicine Cancer Biomarkers Cancer Epidemiology, Biomarkers …Read the Rest

The integration of various “omics” technologies in systems biology for better diagnosis and treatment

October 10, 2013
Systems Biology

With the advancements in the “omics” technologies and the information technology, systems biology has become an important approach for biomarker …Read the Rest

Systems biology approaches for the pharmacokinetic/pharmacodynamic (PK/PD) modeling in drug discovery and development

October 8, 2013
Systems Biology

Systems biology-enabled computational modeling can be useful in almost every step of drug discovery and development, including drug target identification …Read the Rest

Systems biology strategies are useful for biomarker identification in traumatic brain injury (TBI)

October 7, 2013
Systems Biology

The identification of biomarkers may have a significant influence on patient care. Biomarkers may be used for better diagnosis, disease …Read the Rest

Systems biology and “omics” technologies for better drug discovery and outcome studies in cancer treatment

October 3, 2013
Immune

The multiple platforms using the “omics” technologies and the integration of systems biology approaches including both experimental and computational methods …Read the Rest

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Mind-Body, Personalized, and Systems Medicine