Systems Biology

Glucocorticoids, Shift Work, and the Central and Peripheral Clocks

February 27, 2015
Chronobiology

The circadian system can be influenced by both the environment and human activities. For example, shift work can cause a …Read the Rest

Negative Impacts of Electronic Devices on Sleep

January 26, 2015
Chronobiology

The decrease of sleep time and quality in recent decades has led to unhealthy lifestyle and negative impacts on health …Read the Rest

The Effects of Artificial Morning Light on Cognition

January 15, 2015
Chronobiology

Chronic sleep restriction (SR) has detrimental influences on cognitive functions. Although such effects can be reduced by light exposure, it …Read the Rest

The Effects of Melatonin on Sleep Disorders and Pediatric Problems

January 12, 2015
Chronobiology

Melatonin is a hormone produced by the pineal gland. It is chronobiotic and crucial in the regulation of the circadian …Read the Rest

The Database of Biomarkers: Depression – fMRI Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – fMRI Biomarkers •    Potential Biomarkers: Activation patterns: “greater and more sustained signals in three …Read the Rest

The Database of Biomarkers: Depression – EEG Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – EEG Biomarkers •    Potential Biomarkers: “Midline and right frontal (MRF) cortical area,  early decreases …Read the Rest

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – Proteomic and Pathway Biomarkers •    Potential Biomarkers: The tryptophan-kynurenine pathway Detections: Increased indoleamine 2,3-dioxygenase …Read the Rest

The Database of Biomarkers: Depression – Epigenetic Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – Epigenetic Biomarkers •    Potential Biomarkers: “DNA methylation profiles of CpG I at the promoters …Read the Rest

The Database of Biomarkers: Depression – MicroRNA Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: Depression – MicroRNA Biomarkers •    Potential Biomarkers: miR-30e, the polymorphism ss178077483 Potential Applications: Diagnostic biomarker for …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers •    Associated diseases/conditions: Obesity and type 2 diabetes Potential Biomarkers: Serum miR-138, miR-15b, miR-376a …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers – Psychiatric Disorders •    Associated diseases/conditions: Mild Cognitive Impairment (MCI), age-related brain changes Potential …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases

December 9, 2013
Bioinformatics

The Database of Biomarkers: MicroRNA Biomarkers – Cardiovascular Diseases •    Associated diseases/conditions: Atherosclerosis and stroke Potential Biomarkers: Serum miR-21 and …Read the Rest

The Database of Biomarkers: MicroRNA Biomarkers – Cancers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Breast cancer in the Mexican population   Potential Biomarkers: Serum circulating miR-145, miR-155 and miR-382   Potential Applications: …Read the Rest

The Database of Biomarkers: Proteomic and Pathway Biomarkers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Depression   Potential Biomarkers: “Tumor Necrosis Factor (TNF) and its targets in the inflammatory cytokine pathway”   Detections: …Read the Rest

The Database of Biomarkers: Proteomic and Pathway Biomarkers – Cancers

December 9, 2013
Bioinformatics

Associated diseases/conditions: Non-small cell lung cancer (NSCLC)   Potential Biomarkers: Insulin-like growth factor (IGF) pathway   Detections: Protein expressions, serum …Read the Rest

Bioinformatics Databases and Tools for the Discovery of Proteomic and Pathway Biomarkers

December 8, 2013
Bioinformatics

BioLayout (http://www.biolayout.org/) Feature: “For the visualization and analysis of network graphs” Cytoscape (http://www.cytoscape.org/) Feature: “Network visualization” E-Cell (http://www.e-cell.org/) Feature: Computational …Read the Rest

Bioinformatics Resources for MicroRNA (miRNA) Studies and Biomarker Discovery

December 7, 2013
Bioinformatics

CircuitsDB (http://biocluster.di.unito.it/circuits/) Feature: “MicroRNA / Transcription Factor Regulatory Circuits in Human and Mouse” deepBase (http://deepbase.sysu.edu.cn/) Feature: “For annotating and discovering …Read the Rest

The integration of various “omics” technologies in systems biology for better diagnosis and treatment

October 10, 2013
Systems Biology

With the advancements in the “omics” technologies and the information technology, systems biology has become an important approach for biomarker …Read the Rest

Systems biology approaches for the pharmacokinetic/pharmacodynamic (PK/PD) modeling in drug discovery and development

October 8, 2013
Systems Biology

Systems biology-enabled computational modeling can be useful in almost every step of drug discovery and development, including drug target identification …Read the Rest

Systems biology strategies are useful for biomarker identification in traumatic brain injury (TBI)

October 7, 2013
Systems Biology

The identification of biomarkers may have a significant influence on patient care. Biomarkers may be used for better diagnosis, disease …Read the Rest

Systems biology and “omics” technologies for better drug discovery and outcome studies in cancer treatment

October 3, 2013
Immune

The multiple platforms using the “omics” technologies and the integration of systems biology approaches including both experimental and computational methods …Read the Rest

Systems medicine, P4 medicine, and an integrative “Human Model”

October 1, 2013
Systems Biology

Conventional practice in Western medicine focuses on doctors’ “reactive” interventions in response to the occurrence of diseases. With the advancement …Read the Rest

Review of Systems Biology Approaches: Detecting Signaling Pathways in Neurons

September 26, 2013
Nervous System

Temporal dynamics and spatial features are important factors in cell responses including synaptic plasticity. The complex network and interactions among …Read the Rest

Copyright © 2006-2017 PharmTao.com. All Rights Reserved.

Disclaimer: By using this site, the readers agree that the content on our web pages is for information purpose only. The information provided on our web pages is not intended for diagnosis, or to treat, cure or prevent any diseases, conditions or symptoms, or to endorse any products. Personal directions and the use of health products should be provided by qualified health professionals.

Mind-Body, Personalized, and Systems Medicine