Category Archives: Psychiatric Genetics

Psychiatric Genetics Database

Psychoneuroimmunology and Nutrition Books

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Healing Stress and Chronic Diseases: Mind-Body Methods and Mechanisms (Psychoneuroimmunology) Vitamins and Weight Loss: How Vitamins Affect Fat Burning Exercises, Bariatric Surgery, and Obesity Related Diseases Natural Antioxidants and Weight … Continue reading

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Alzheimer’s Disease and the Gene APOE (Apolipoprotein E)

The APOE gene has other symbols as “AD2”, “LPG”, “APO-E”, and “LDLCQ5”. It is located at 19q13.2. The APOE gene has important roles in cardiovascular diseases including myocardial infarction, ischemic stroke, and coronary heart disease (Kathiresan et al. 2008). The … Continue reading

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Psychiatric Symptoms and the Gene SGCE (Sarcoglycan Epsilon)

The SGCE gene has other symbols as “ESG” and “DYT11”. It is located at 7q21.3. As a member of the sarcoglycan family, it is a component of the dystrophin-glycoprotein complex (DGC). It provides the connections between the actin cytoskeleton and … Continue reading

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Epilepsy and the Gene KCNT1 (Potassium Sodium-Activated Channel Subfamily T member 1)

The KCNT1 gene has other symbols as “ENFL5”, “SLACK”, “EIEE14”, “KCa4.1”, “Slo2.2”, and “bA100C15.2”. It is located at 9q34.3. Encoding a sodium-activated potassium channel, this gene is highly expressed in the brain (Nagase et al. 2000). It has been related … Continue reading

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Neuropsychiatric Disorders and the Gene COMT (Catechol-O-Methyltransferase)

The COMT gene has another symbol as “HEL-S-98n”. It is located at 22q11.21. It is an important enzyme in the process of metabolic degradation of catecholamines (Gogos et al., 1998). The 158met variant on the nondeleted allele has been related … Continue reading

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Psychiatric Diseases and the Gene DISC1 (Disrupted in Schizophrenia 1)

The DISC1 gene has other symbols as “SCZD9” and “C1orf136”. It is located at 1q42.2. It is involved in the regulation of the AKT-mTOR signaling pathway and associated with embryonic and adult neurogenesis (Kim et al. 2009). DISC1 has been … Continue reading

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Stress, Depression, Inflammation, and Personalized Medicine

Stress, Depression, Inflammation, and Personalized Medicine Psychological stress has been associated with higher levels of inflammation and the risks of many physical disorders including heart diseases. For example, chronic stress responses may cause a variety of skin disorders including allergic … Continue reading

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Stress, Chronic Diseases, and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Although many chronic diseases such as cancer are apparently physical, they can lead to psychological distress. Chronic psychosocial stress may in turn affect the physical health negatively. Studies in psychoneuroimmunology (PNI) have shown that the … Continue reading

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Systems Biology and Neurodegenerative Diseases

Neurodegenerative diseases (NDs) are complex disorders that affect more than 40 million people globally (Wood et al., 2015). The multifaceted variations in the pathophysiology of the diseases make it difficult for effective therapy or prevention of the disease progression. More … Continue reading

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Systems Biology, miRNAs, and Alzheimer’s Disease

Neurodegenerative diseases such as Alzheimer’s disease (AD) are multifactorial involving genomics, metabolomics, epigenomics, transcriptomics, interactomics, as well as environmental components. Systemic understanding of these complex diseases may start with the alterations in the cellular networks. Investigation in integrative systems biology … Continue reading

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