Category Archives: Immune

Immune system

Cytokines, Depression, and Psychoneuroimmunology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Cytokines such as interferon (IFN)-alpha may cause dopamine depletion and affect the pathways of monoamine metabolism. Their alterations may result in behavioral changes including depression, psychomotor slowing, and fatigue (Miller, … Continue reading

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What is Psychodermatology

Stress, Chronic Diseases, and Psychoneuroimmunology Stress, Depression, Inflammation, and Psychoneuroimmunology Skin disorders are often associated with psychological conditions such as stress and anxiety. With more and more evidences linking mind and body, some novel disciplines are emerging, such as Psychodermatology. … Continue reading

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Effects of Mindfulness Meditation on the Immune System in HIV Patients

Mindfulness meditation training has been found to reduce stress in different patient populations. Researchers at the University of California, Los Angeles studied the effects of meditation on CD4+ T lymphocyte counts in stressed HIV-infected adults (Creswell et al., 2009). In … Continue reading

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The Interactions between Natural Killer Cells and Monocytes in Anti-Cancer Therapies

Human natural killer (NK) cells, monocytes, and dendritic cells are important components of the innate immune functions with instant protections against cancer cells and infections. Monocytes are large white blood cells (also called leukocytes). They can become macrophages and obtain … Continue reading

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Inflammation and Diseases

Inflammation is an immune response of the body to protect from irritants, stimuli, or external materials that may be detrimental. Inflammatory signs: Redness Swelling Heat Pain Immune surveillance: The immune system can monitor, find, and remove the useless or damaging … Continue reading

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Systems biology and “omics” technologies for better drug discovery and outcome studies in cancer treatment

The multiple platforms using the “omics” technologies and the integration of systems biology approaches including both experimental and computational methods would support both drug target discovery and clinical outcome studies, especially in cancer treatment. For instance, immunotherapies have become an … Continue reading

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Psychosocial Factors and Cancer Progression: Psychoneuroimmunology (PNI) Mechanisms

Psychosocial factors have been found to play important roles in the development of various diseases, including cancer progression. Such associations are mediated via the biobehavioral pathways in various patient populations, including the hematopoietic stem cell transplant (HCT) patients (Knight et … Continue reading

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The Database of Cytokine Receptors: L – P

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions LIFR SWS; SJS2; STWS; CD118; LIF-R; FLJ98106; FLJ99923 LEUKEMIA INHIBITORY FACTOR RECEPTOR   NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser … Continue reading

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The Database of Cytokine Receptors: I

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IFNAR1 AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC INTERFERON, ALPHA, BETA, AND OMEGA, RECEPTOR 1 IFNAR ANTIVIRAL PROTEIN, ALPHA TYPE; AVP ANTIVIRAL PROTEIN, BETA TYPE … Continue reading

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The Database of Cytokine Receptors: C

Symbol Other Symbols Name Other Names Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions CCR2   chemokine (C-C motif) receptor 2 CKR2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2 NCBI Gene Map Viewer HPRD SNP: Genotype … Continue reading

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The Cytokine Database: T – X

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions TNFRSF11B OPG; TR1; OCIF; MGC29565 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 11B NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser     … Continue reading

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The Cytokine Database: O – S

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways OSM MGC20461 ONCOSTATIN M NCBI Gene OMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics Association DB GWAS Central HGVS MutaDATABASE SNP SNP: … Continue reading

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The Cytokine Database: M – N

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions MDK MK; NEGF2; FLJ27379 MIDKINE NCBI GeneOMIM EnsemblNCBI Map Viewer UCSC Genome Browser UniProtHPRD Genetics Association DBGWAS Central HGVS MutaDATABASE SNP SNP: GeneView KEGG … Continue reading

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The Cytokine Database: ISG – L

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways ISG15 G1P2; IP17; UCRP; IFI15; hUCRP UBIQUITIN-LIKE MODIFIER ISG15 NCBI GeneOMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics Association DBGWAS CentralHGVS MutaDATABASE … Continue reading

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The Cytokine Database: Interleukins

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IL1A IL1; IL-1A; IL1F1; IL1-ALPHA INTERLEUKIN 1-ALPHA NCBI GeneOMIM Ensembl NCBI Map ViewerUCSC Genome Browser UniProt HPRD Genetics Association DBGWAS CentralHGVSMutaDATABASE SNP SNP: GeneView … Continue reading

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The Cytokine Database: Interferons

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions IFNA1 IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; MGC138207; MGC138505; MGC138507; IFN-alphaD INTERFERON, ALPHA-1 NCBI GeneOMIM Ensembl NCBI Map Viewer UCSC Genome Browser UniProt HPRD Genetics … Continue reading

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The Cytokine Database: D – F

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions DMKN UNQ729; ZD52F10; FLJ79374 Dermokine 93099 Genome ProteinHPRD SNPSNP: GeneView KEGG EBI3 IL27B; IL-27B EPSTEIN-BARR VIRUS-INDUCED GENE 3 NCBI GeneOMIM Ensembl NCBI Map ViewerUCSC … Continue reading

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The Cytokine Database: A – C

Gene Other Symbols Full Name Gene Information Genome Information Protein Information Genetic Variants Cellular Pathways Functions AIMP1 p43; HLD3; EMAP2; SCYE1; EMAPII AMINOACYL-tRNA SYNTHETASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 NCBI GeneOMIM EnsemblNCBI Map ViewerUCSC Genome Browser UniProtHPRD     Genetics Association … Continue reading

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