Category Archives: Neuroinformatics
Microglia, Polydendrocytes, Ependymal cells, and the Embryonic Neural Tube
Microglia are macrophages in the brain. Macrophages are the immune cells in the blood and other parts of the body. Microglia can be activated upon neuronal damages or infections, to destroy foreign stuff or pathogens, as well as necrotic tissues. … Continue reading
Glia, Astrocytes, Oligodendrocytes, and Schwann Cells
Glia have a close relationship with neurons but this relationship has not been fully understood. Glia are essential partners to neurons and may influence many functions including neuronal and metabolic activities, neurotransmitter kinetics, as well as the blood flow. Glial … Continue reading
Synapses, Gap Junctions, and Glia: Their Structures, Functions, and Features
Synapses are the regions between the terminal of an axon and the receptors on other cells. Neurotransmitters can bring the messages across the synapses. Synapses can be open or enclosed, large or small. Synaptic inputs can affect the neuron activities. … Continue reading
Structure of the Neurons: Dendrites, Axons, and Membrane Potentials
Types of cells in the nervous system There are two types of cells in the nervous system. One type of cells are called neurons, the other type of cells are called glia. Studies have found that there are about 86 … Continue reading
Neuroscience Data and Neuroinformatics
Neuroscience Data and Neuroinformatics Neuroscience Data At least 50% genes of the mammalian genome are expressed by the nervous system (Sutcliffe et al., 1991). To understand brain-related diseases, it is necessary to map and study the expression patterns … Continue reading
Neuroinformatics Software and Ontology Tools
Neuroinformatics Software and Ontology Tools Category Source Name Purposes/Features/Methods Contents Applications URL References Neuroimaging Informatics Tools BrainVisa (BV) For high resolution MR images To quantify global and regional variances About cortical anatomy A plug-in application for structural analysis … Continue reading
Neuroinformatics Databases about the Brain: Different Species
Neuroinformatics Databases about the Brain: Different Species Species Source Name Purposes/Features/Methods Contents Applications URL References Mouse 3D digital atlas database of the mouse brain Lower spatial resolution images were utilized to enhance time efficiency for morphological phenotyping The in … Continue reading
Neuroinformatics Databases about the Brain-Related Diseases
Neuroinformatics Databases about the Brain-Related Diseases Disease Source Name Purposes/Features/Methods Contents Applications URL References Autism National Database for Autism Research (NDAR) A secure database for data sharing, data harmonization, and collaboration in autism spectrum disorder researchers Data from more than … Continue reading
Neuroinformatics Databases for the Structure-Function Studies of the Brain
Neuroinformatics Databases for the Structure-Function Studies of the Brain Category Source Name The Needs/Challenges Purposes/Features/Methods Contents Applications URL References Neuroinformatics Databases about the Brain Structures The Internet Brain Volume Database (IBVD) Available data from neuroanatomic volumetric measurements; Various … Continue reading
Neuroinformatics: An Introduction
Neuroinformatics: An Introduction The challenges in neuroinformatics Challenges in making neuroinformatics databases and tools (Morse, 2008) The variety in spatial scales Various data types Traditional bioinformatics concentrates on Genomic and proteomic data Sequences (DNA, RNA, and protein molecules) Development … Continue reading
