Monthly Archives: January 2021

Host Factors and Antiviral Targets

Host Factors and Antiviral Targets (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Host factors associated with SARS-CoV replication need to be investigated (de Wilde et al., 2015). These factors include the innate immune response and … Continue reading

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Saikosaponins and Coronaviruses

Saikosaponins (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Saikosaponins are oleanane derivatives including glucosides (Cheng et al., 2006). Saikosaponins are extracted from plants such as Bupleurum spp., Heteromorpha spp. and Scrophularia scorodonia. Saikosaponins have anti-inflammatory … Continue reading

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Antiviral Compounds and Human Coronavirus OC43

Antiviral Compounds and Human Coronavirus OC43 (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Stephania tetrandra and Menispermaceae contain the bis-benzylisoquinoline alkaloids tetrandrine (TET) (Kim et al., 2019). They also have fangchinoline (FAN) and cepharanthine (CEP). … Continue reading

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Herbal Extracts May Inhibit Coronavirus Replication

Herbal Extracts May Inhibit Coronavirus Replication (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Medicinal herbal extracts have been screened for their antiviral effects on coronavirus replication (Kim et al., 2008; Kim et al., 2010). The … Continue reading

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Antiviral Flavonoids from Houttuynia Cordata

Antiviral Flavonoids from Houttuynia Cordata (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) The ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) may have antiviral effects. It may be used against coronaviruses and … Continue reading

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Sabadinine, Houttuynia Cordata, and Coronaviruses

Sabadinine and Houttuynia Cordata (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) The replication of CoVs relies on proteolytic processing (Toney et al., 2004). The major proteinase, 3C-like protease (3CLpro), may become a target for anti-SARS … Continue reading

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Glycyrrhizin, Cinnamomi Cortex, and Toona Sinensis Roem

Glycyrrhizin, Cinnamomi Cortex, and Toona Sinensis Roem (From Potential Antiviral Agents for Coronaviruses: Compounds, Herbal Products, and Drug Targets) Glycyrrhizin (GL) may suppress SARS-CoV replication (Hoever et al., 2005). The insertion of 2-acetamido-beta-d-glucopyranosylamine into the GL glycoside chain increased the … Continue reading

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