Monthly Archives: September 2015

Systems Biology and Neurodegenerative Diseases

Neurodegenerative diseases (NDs) are complex disorders that affect more than 40 million people globally (Wood et al., 2015). The multifaceted variations in the pathophysiology of the diseases make it difficult for effective therapy or prevention of the disease progression. More … Continue reading

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Systems Biology and Drug Screening

Conventional drug design mostly uses the ligand and structure-based approaches (Prathipati and Mizuguchi, 2015). With the advancement in functional genomics and the availability of high-throughput (HTP) data, information on interactive molecular networks can be used to analyze the efficacy and … Continue reading

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The Circadian Clock, Genes, and Systems Biology

The circadian clock is essential in many organisms. The circadian timing system enables the physiological and behavioral adaptation to the external geophysical changes through the regulation of the temporal cellular processes (Lehmann et al., 2015). In mammals, the master pacemaker … Continue reading

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