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Glycerol efflux from adipocytes to the liver is crucial for lipid and glucose homeostasis. Aquaporin 7 (AQP7) is a glycerol channel serving as a gateway of glycerol release and a regulator of adipocyte metabolism. A study done by Catalan et al. measured the gene expression of AQP7 in visceral adipose tissue (VAT) and AQP9 in liver [...] ABCA1 (ATP-binding cassette sub-family A (ABC1) member 1) is one of the most important cellular cholesterol transporters in charge of removing cholesterol from the body through cholesterol efflux. Mutations of this gene have been associated with high-density-lipoprotein (HDL) deficiency, Tangier disease and familial hypoalphalipoproteinemia. In Chinese overweight and obese patients, the expression of ABCA1 in monocytes [...] Full Name: ATP-binding cassette, sub-family A (ABC1), member 3 [Homo sapiens] Symbol: ABCA3 Other Symbols: ABC-C, ABC3, EST111653, LBM180, MGC166979, MGC72201, SMDP3 Other Names: ABC transporter 3; ATP-binding cassette, sub-family A member 3 Chromosome Location: 16p13.3 Map Viewer Gene ID: 21 OMIM ID: 601615 OMIM Family : ATP-binding cassette, sub-family A Classification: 3.A.1.211.5 Sequences: Nucleotide Protein Functions: Development of resistance to xenobiotics, engulfment during programmed cell death Polymorphisms/Variants/SNPs/Pharmacogenomics: SNP SNP VarView GeneView in dbSNP Pathways and Cellular Interactions: ATPase activity induced by [...]
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