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Diseases: Obesity: Aquaporin 7 (AQP7) May Be Altered

Glycerol efflux from adipocytes to the liver is crucial for lipid and glucose homeostasis. Aquaporin 7 (AQP7) is a glycerol channel serving as a gateway of glycerol release and a regulator of adipocyte metabolism.

A study done by Catalan et al. measured the gene expression of AQP7 in visceral adipose tissue (VAT) and AQP9 in liver [...]

December 11th, 2009 | Tags: , , , , , , , , , | Category: Obesity | Comments are closed

Diseases: Obesity: ABCA1

ABCA1 (ATP-binding cassette sub-family A (ABC1) member 1) is one of the most important cellular cholesterol transporters in charge of removing cholesterol from the body through cholesterol efflux. Mutations of this gene have been associated with high-density-lipoprotein (HDL) deficiency, Tangier disease and familial hypoalphalipoproteinemia.

In Chinese overweight and obese patients, the expression of ABCA1 in monocytes [...]

December 10th, 2009 | Tags: , , , , , , , , , , , , | Category: Obesity | Comments are closed

Gene List: Other Transporters

Transporters not included in other families:

Gene Symbol/Link; Other Symbols; Full Name; Other Names

ASNA1; ARSA-I, ARSA1, MGC3821; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

CD68; DKFZp686M18236, GP110, SCARD1; CD68 molecule

CTNS; CTNS-LSB, PQLC4; cystinosis, nephropathic

DISP1; DISPA, DKFZp434I0428, FLJ43740, MGC104180, MGC13130, MGC16796; dispatched homolog 1 (Drosophila)

HMGCR; LDLCQ3; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase

LAMP1; CD107a, LAMPA, LGP120; lysosomal-associated membrane protein 1

LAMP2; CD107b, [...]

December 9th, 2009 | Tags: , , , , , , | Category: Transporter List | Comments are closed
 
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