Membrane Transporter Database for Personalized Medicine » genetic basis http://pharmtao.com/blog5 Databases and Encyclopedia of Transporters, Translational Medicine, Drug Discovery and Development Sat, 03 Apr 2010 00:42:11 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Diseases: Obesity: ABCA1 and ABCB1 http://pharmtao.com/blog5/2009/12/10/diseases-obesity-abca1/ http://pharmtao.com/blog5/2009/12/10/diseases-obesity-abca1/#comments Fri, 11 Dec 2009 01:00:09 +0000 PharmTao.com http://pharmtao.com/blog5/?p=104 ABCA1 (ATP-binding cassette sub-family A (ABC1) member 1) is one of the most important cellular cholesterol transporters in charge of removing cholesterol from the body through cholesterol efflux. Mutations of this gene have been associated with high-density-lipoprotein (HDL) deficiency, Tangier disease and familial hypoalphalipoproteinemia.

In Chinese overweight and obese patients, the expression of ABCA1 in monocytes [...]]]> http://pharmtao.com/blog5/2009/12/10/diseases-obesity-abca1/feed/ 0