Diseases: Obesity: ABCA1

ABCA1 (ATP-binding cassette sub-family A (ABC1) member 1) is one of the most important cellular cholesterol transporters in charge of removing cholesterol from the body through cholesterol efflux. Mutations of this gene have been associated with high-density-lipoprotein (HDL) deficiency, Tangier disease and familial hypoalphalipoproteinemia.

In Chinese overweight and obese patients, the expression of ABCA1 in monocytes [...]

Gene List: Other Transporters

Transporters not included in other families:

Gene Symbol/Link; Other Symbols; Full Name; Other Names

ASNA1; ARSA-I, ARSA1, MGC3821; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

CD68; DKFZp686M18236, GP110, SCARD1; CD68 molecule

CTNS; CTNS-LSB, PQLC4; cystinosis, nephropathic

DISP1; DISPA, DKFZp434I0428, FLJ43740, MGC104180, MGC13130, MGC16796; dispatched homolog 1 (Drosophila)

HMGCR; LDLCQ3; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase

LAMP1; CD107a, LAMPA, LGP120; lysosomal-associated membrane protein 1

LAMP2; CD107b, [...]

Gene List: Solute Carrier Family (SLC)

Gene Symbol/Link; Other Symbols; Full Name

SLC1A1; RP11-6J24.1, EAAC1, EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

SLC1A2; EAAT2, GLT-1; solute carrier family 1 (glial high affinity glutamate transporter), member 2

SLC1A3; EA6, EAAT1, FLJ25094, GLAST, GLAST1; solute carrier family 1 (glial high affinity glutamate transporter), member 3

SLC1A4; ASCT1, SATT; solute [...]

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