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ABCA1 Transporter - Pathways and Cellular Interactions

ABCA1 Transporter – Pathways and Cellular Interactions

ABCA1 is involved in cellular lipid removal pathways.

Alzheimer’s disease:

Interaction between HMGCR and ABCA1 cholesterol-related genes modulates Alzheimer’s disease risk. Rodríguez-Rodríguez E, Mateo I, Infante J, Llorca J, García-Gorostiaga I, Vázquez-Higuera JL, Sánchez-Juan P, Berciano J, Combarros O. Brain Res. 2009 Jul 14;1280:166-71. Epub 2009 May 14. PMID: 19446537

Apolipoprotein:

The [...]

November 3rd, 2009 | Tags: , , , , , , , , , , , , | Category: Pathways | Leave a comment

ABCA1 - Structure-Function Associations

ABCA1 – Structure-Function Associations

Transition from dimers to higher oligomeric forms occurs during the ATPase cycle of the ABCA1 transporter. Trompier D, Alibert M, Davanture S, Hamon Y, Pierres M, Chimini G. J Biol Chem. 2006 Jul 21;281(29):20283-90. PMID: 16709568

Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids. Vedhachalam C, Liu L, Nickel M, [...]

November 3rd, 2009 | Tags: , , , , , , , , , | Category: Structure-Function | Leave a comment

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