Membrane Transporter Database for Personalized Medicine » ATP-binding cassette

Diseases: Obesity: ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)

PharmTao.com — Thu, 25 Mar 2010 04:29:04 +0000

ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)

[ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-GP, PGY1]

This gene belongs to the superfamily of ATP-binding cassette (ABC) transporters, and the MDR/TAP subfamily. It is an ATP-dependent drug efflux pump for xenobiotic compounds. It is associated with decreased drug accumulation in multidrug-resistant cells and the development of resistance to [...]

Diseases: Obesity: ABCA1 and ABCB1

PharmTao.com — Fri, 11 Dec 2009 01:00:09 +0000

ABCA1 (ATP-binding cassette sub-family A (ABC1) member 1) is one of the most important cellular cholesterol transporters in charge of removing cholesterol from the body through cholesterol efflux. Mutations of this gene have been associated with high-density-lipoprotein (HDL) deficiency, Tangier disease and familial hypoalphalipoproteinemia.

In Chinese overweight and obese patients, the expression of ABCA1 in monocytes [...]

Gene List: The ATP-binding Cassette (ABC) Superfamily (Classification: 3.A.1.)

PharmTao.com — Tue, 08 Dec 2009 00:58:52 +0000

Gene Symbol/Link; Other Symbols; Full Name

ABCA1; ABC-1, ABC1, CERP, FLJ14958, HDLDT1, MGC164864, MGC165011, TGD; ATP-binding cassette, sub-family A (ABC1), member 1

ABCA2; RP11-229P13.8, ABC2, MGC129761; ATP-binding cassette, sub-family A (ABC1), member 2

ABCA3; ABC-C, ABC3, EST111653, LBM180, MGC166979, MGC72201, SMDP3; ATP-binding cassette, sub-family A (ABC1), member 3

ABCA4; ABC10, ABCR, ARMD2, CORD3, DKFZp781N1972, FFM, FLJ17534, RMP, RP19, [...]