ABCA1 – Structure-Function Associations
Transition from dimers to higher oligomeric forms occurs during the ATPase cycle of the ABCA1 transporter. Trompier D, Alibert M, Davanture S, Hamon Y, Pierres M, Chimini G. J Biol Chem. 2006 Jul 21;281(29):20283-90. PMID: 16709568
Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids. Vedhachalam C, Liu L, Nickel M, [...]
ABCA1
Polymorphisms/Variants/SNPs/Pharmacogenomics
dbSNP
SNP VarView
GeneView in dbSNP
Prediction:
Accurate prediction of the functional significance of single nucleotide polymorphisms and mutations in the ABCA1 gene. Brunham LR, Singaraja RR, Pape TD, Kejariwal A, Thomas PD, Hayden MR. PLoS Genet. 2005 Dec;1(6):e83. Epub 2005 Dec 30. PMID: 16429166
Alzheimer’s Disease:
A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer’s disease [...]