Full Name:
ATP-binding cassette, sub-family A (ABC1), member 3 [Homo sapiens]
Symbol:
ABCA3
Other Symbols:
ABC-C, ABC3, EST111653, LBM180, MGC166979, MGC72201, SMDP3
Other Names:
ABC transporter 3; ATP-binding cassette, sub-family A member 3
Chromosome Location:
16p13.3
Map Viewer
Gene ID:
21
OMIM ID:
601615
OMIM
Family :
ATP-binding cassette, sub-family A
Classification:
3.A.1.211.5
Sequences:
Nucleotide
Protein
Functions:
Development of resistance to xenobiotics, engulfment during programmed cell death
Polymorphisms/Variants/SNPs/Pharmacogenomics:
SNP
SNP VarView
GeneView in dbSNP
Pathways and Cellular Interactions:
ATPase activity induced by [...]
Full Name:
ATP-binding cassette, sub-family A (ABC1), member 2 [Homo sapiens]
Symbol:
ABCA2
Other Symbols:
RP11-229P13.8, ABC2, MGC129761
Other Names:
ATP-binding cassette, sub-family A, member 2
Chromosome Location:
9q34
Map Viewer
Gene ID:
20
OMIM ID:
600047
OMIM
Family :
ATP-binding cassette, sub-family A
Classification:
3.A.1.211.3
Sequences:
Nucleotide
Protein
Functions:
Macrophage lipid metabolism, neural development
Polymorphisms/Variants/SNPs/Pharmacogenomics:
SNP
SNP VarView
Pathways and Cellular Interactions:
Neural transmembrane lipid export. (http://www.ncbi.nlm.nih.gov/pubmed/12363033)
Tissue Distribution:
Brain, liver, kidney, macrophages, oligodendrocytes
Relevant Diseases:
Mutations and polymorphisms have been [...]
ABCA1 Transporter: Disease Association:
Coronary Disease:
- The R219K polymorphism of ABCA1 is related with altered lipoprotein levels, and may affect the high-density lipoprotein-cholesterol (HDL-C) response to pravastatin in Chinese patients with coronary heart disease (CHD).
(Effect of R219K polymorphism of the ABCA1 gene on the lipid-lowering effect of pravastatin in Chinese patients with coronary heart disease. Li [...]
