Influenza Database for Personalized Medicine » PI3K http://pharmtao.com/blog4 Databases, Encyclopedia, and All Information for Influenza Prevention and Treatment Sun, 29 Nov 2009 23:43:09 +0000 http://wordpress.org/?v=2.8.6 en hourly 1 The PI3K/Akt signaling pathway supports influenza viral propagation http://pharmtao.com/blog4/2009/11/27/the-pi3kakt-signaling-pathway-supports-influenza-viral-propagation/ http://pharmtao.com/blog4/2009/11/27/the-pi3kakt-signaling-pathway-supports-influenza-viral-propagation/#comments Fri, 27 Nov 2009 21:16:05 +0000 PharmTao.com http://pharmtao.com/blog4/?p=207 Pathways:

PI3K/Akt signaling pathway

Host Molecules Involved:

Phosphatidylinositol-3-kinase (PI3K), the downstream effector protein kinase Akt

Viral Molecules Involved:

NS1

Tissues:

Influenza A virus-infected cells

Interactions:

PI3K is activated through direct interaction with A/NS1, via the p85 regulatory subunit.

Mechanisms:

PI3K/Akt signaling is required for functions during infection. The kinase activates the interferon regulatory [...]]]> http://pharmtao.com/blog4/2009/11/27/the-pi3kakt-signaling-pathway-supports-influenza-viral-propagation/feed/ 0