|
||||||
|
Pathways: IFN-gamma pathway Host Molecules Involved: Protease-activated receptor-2 (PAR(2)), associated with inflammation at mucosal surfaces. Tissues: Respiratory tract, mucosal surfaces, bronchoalveolar lavages Systems: Lungs, immune system Interactions: PAR(2) enhances IFN- gamma production. Mechanisms: In vitro, PAR(2) inhibits influenza virus type A (IAV) replication through the production of IFN-gamma. Gene: SFTPD Full Name: surfactant protein D [Homo sapiens] Other Symbols: COLEC7, PSP-D, SFTP4, SP-D Other Names: collectin 7; pulmonary surfactant apoprotein; pulmonary surfactant-associated protein D; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4 Chromosome Location: 10q22.2-q23.1 OMIMID: 178635 GeneID: 6441 Sequences: Nucleotide Human-Influenza Interactions: - An extended ligand binding site is found for mannosylated ligands on SFTPD, with [...] Symbol: CCL11 Name: chemokine (C-C motif) ligand 11 [Homo sapiens] Other Symbols: MGC22554, SCYA11 Other Names: eosinophil chemotactic protein; eotaxin-1; small inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) Chromosome Location: 17q21.1-q21.2 OMIMID: 601156 GeneID: 6356 Sequences: Nucleotide Protein Family: Cytokines Function: Chemotactic activity for eosinophils; associated with eosinophilic inflammatory diseases, e.g., atopic dermatitis, allergic rhinitis, asthma [...]
Copyright © 2009 PharmTao.com. All Rights Reserved.
|
||||||
|
Copyright © 2010 Influenza Database for Personalized Medicine - All Rights Reserved 
|
||||||
