Archives

SOCS3

Gene:

SOCS3

Full Name:

suppressor of cytokine signaling 3 [Homo sapiens]

Other Symbols:

ATOD4, CIS3, Cish3, MGC71791, SOCS-3, SSI-3, SSI3

Other Names:

STAT induced STAT inhibitor 3; cytokine-induced SH2 protein 3

Chromosome Location:

17q25.3

OMIMID:

604176

GeneID:

9021

Sequences:

Nucleotide
Protein

Human-Influenza Interactions:

SOCS1 and SOCS3 regulate influenza A virus-triggered innate immune responses through inhibiting type I interferon receptor [...]

SOCS1

Gene:

SOCS1

Full Name:

suppressor of cytokine signaling 1 [Homo sapiens]

Other Symbols:

CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3

Other Names:

JAK binding protein; STAT induced SH3 protein 1; Tec-interacting protein 3; cytokine-inducible SH2 protein 1

Chromosome Location:

16p13.13

OMIMID:

603597

GeneID:

8651

Sequences:

Nucleotide
Protein

Human-Influenza Interactions:

SOCS1 and SOCS3 regulate influenza A virus-triggered innate immune responses through inhibiting [...]

Host-Virus (Human-Influenza) Interaction Genes: IFNB1

Symbol:

IFNB1

Full Name:

interferon, beta 1, fibroblast [Homo sapiens]

Other Symbols:

IFB, IFF, IFNB, MGC96956

Other Names:

interferon beta

Chromosome Location:

9p21

OMIMID:

147640

GeneID:

3456

Sequences:

Nucleotide
Protein

Family:

Interferon

Human-Influenza Interactions:

- After influenza virus infection, strong tissue-specific induction of IFN-beta gene keeps immune cells in activated state.

(http://www.ncbi.nlm.nih.gov/pubmed/19667093)

- Influenza A viruses inhibit IFNbeta gene induction, and suppress type I IFN [...]

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