Archives

IL29

Symbol:

IL29

Full Name:

interleukin 29 (interferon, lambda 1) [Homo sapiens]

Other Symbols:

IFNL1, IL-29

Other Names:

interferon, lambda 1; interleukin 29

Chromosome Location:

19q13.13

OMIMID:

607403

GeneID:

282618

Sequences:

Nucleotide
Protein

Family:

Interferons

Function:

Expression induced by viral infection.

Human-Influenza Interactions:

During influenza A virus infection, in alveolar type II cells, IL-29 mediates IFN-beta-independent protection through activation of antiviral genes.

(http://www.ncbi.nlm.nih.gov/pubmed/19155475)

Host-Virus (Human-Influenza) Interaction Genes: IFNB1

Symbol:

IFNB1

Full Name:

interferon, beta 1, fibroblast [Homo sapiens]

Other Symbols:

IFB, IFF, IFNB, MGC96956

Other Names:

interferon beta

Chromosome Location:

9p21

OMIMID:

147640

GeneID:

3456

Sequences:

Nucleotide
Protein

Family:

Interferon

Human-Influenza Interactions:

- After influenza virus infection, strong tissue-specific induction of IFN-beta gene keeps immune cells in activated state.

(http://www.ncbi.nlm.nih.gov/pubmed/19667093)

- Influenza A viruses inhibit IFNbeta gene induction, and suppress type I IFN [...]

Host-Virus (Human-Influenza) Interaction Genes: IFNAR1

Symbol:

IFNAR1

Full Name:

interferon (alpha, beta and omega) receptor 1 [Homo sapiens]

Other Symbols:

AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC

Other Names:

alpha-type antiviral protein; beta-type antiviral protein; interferon-alpha receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1

Chromosome Location:

21q22.11

OMIMID:

107450

GeneID:

3454

Sequences:

Nucleotide
Protein

Family:

Interferon

Function:

An antiviral factor; stimulates Janus protein kinases.

Human-Influenza Interactions:

In influenza A virus-infected bronchial epithelial [...]

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