Pathways:
Toll-like receptor (TLR) signaling pathways
Host Molecules Involved:
TLR-3 is involved in antiviral and inflammatory responses of the innate immunity in response to influenza infections.
Other Molecules:
Poly ICLC, a synthetic double stranded RNA, polyriboinosinic-poly ribocytidylic acid (Poly IC) stabilized with l-lysine (L) and carboxymethylcellulose [...]
Gene:
IVNS1ABP
Full Name:
influenza virus NS1A binding protein [Homo sapiens]
Other Symbols:
RP4-635A23.5, DKFZp686K06216, FLARA3, FLJ10069, FLJ10411, FLJ10962, FLJ35593, FLJ36593, HSPC068, KIAA0850, ND1, NS-1, NS1-BP, NS1BP
Other Names:
NCX downstream gene 1; NS1-binding protein; aryl hydrocarbon receptor-associated 3
Chromosome Location:
1q25.1-q31.1
OMIMID:
609209
GeneID:
10625
Sequences:
Nucleotide
Protein
Human-Influenza Interactions:
Alpha-enolase and its MBP-1 variant are involved in maintaining [...]
Symbol:
IFNG
Full Name:
interferon, gamma [Homo sapiens]
Other Symbols:
IFG, IFI
Chromosome Location:
12q14
OMIMID:
147570
GeneID:
3458
Sequences:
Nucleotide
Protein
Family:
Interferon
Function:
Antiviral, immunoregulatory, anti-tumor; a potent activator of macrophages.
Human-Influenza Interactions:
In response to influenza and vaccinia antigens, expression was observed in CD8+ T cells of patients with advanced solid tumors.
(http://www.ncbi.nlm.nih.gov/pubmed/15624893)
