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Host-Virus (Human-Influenza) Interaction Genes: CASP1

Symbol:

CASP1

Full Name:

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) [Homo sapiens]

Other Symbols:

ICE, IL1BC, P45

Other Names:

CASP1 nirs variant 1; IL1B-convertase; caspase 1; caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase); caspase-1; interleukin 1-B converting enzyme; interleukin 1-beta convertase

Chromosome Location:

11q23

OMIMID:

147678

GeneID:

834

Sequences:

Nucleotide

Protein

Family:

Cysteine-aspartic acid protease [...]

Host-Virus (Human-Influenza) Interaction Genes: BAX

Gene:

BAX

Name:

BCL2-associated X protein [Homo sapiens]

Other Symbols:

BCL2L4

Other Names:

apoptosis regulator BAX

Chromosome Location:

19q13.3-q13.4

OMIM ID:

600040

GeneID:

581

Sequences:

Nucleotide

Protein

Family:

BCL2 family

Function:

An apoptotic activator.

Pathways:

Involved in P53-mediated apoptosis.

Human-Influenza Interactions:

Functional Bax is required for influenza A virus to establish an apoptotic response.

(http://www.ncbi.nlm.nih.gov/pubmed/19494020)

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