Pathways:
Toll-like receptor (TLR) signaling pathways
Host Molecules Involved:
TLR-3 is involved in antiviral and inflammatory responses of the innate immunity in response to influenza infections.
Other Molecules:
Poly ICLC, a synthetic double stranded RNA, polyriboinosinic-poly ribocytidylic acid (Poly IC) stabilized with l-lysine (L) and carboxymethylcellulose [...]
Gene:
TNFSF4
Full Name:
tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens]
Other Symbols:
CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Other Names:
CD134 ligand; OX40 antigen ligand; tax-transcriptionally activated glycoprotein 1 (34kD)
Chromosome Location:
1q25
OMIMID:
603594
GeneID:
7292
Sequences:
Nucleotide
Protein
Human-Influenza Interactions:
OX40L costimulates human antiviral memory CD8 T cell responses, enhances anti-influenza responses, especially in combination [...]
Gene:
PTX3
Full Name:
pentraxin-related gene, rapidly induced by IL-1 beta [Homo sapiens]
Other Symbols:
TNFAIP5, TSG-14
Other Names:
pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5; pentaxin-related protein PTX3; pentraxin 3; pentraxin-3; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14
Chromosome Location:
3q25
OMIMID:
602492
GeneID:
5806
Sequences:
Nucleotide
Protein [...]
