Influenza Database for Personalized Medicine » Host-Virus Interactions

XDH

PharmTao.com — Thu, 26 Nov 2009 05:31:10 +0000

Gene:

XDH

Full Name:

xanthine dehydrogenase [Homo sapiens]

Other Symbols:

XO, XOR

Other Names:

xanthene dehydrogenase; xanthine oxidase; xanthine oxidoreductase

Chromosome Location:

2p23.1

OMIMID:

607633

GeneID:

7498

Sequences:

Nucleotide Protein

Human-Influenza Interactions:

Defects in xanthine dehydrogenase lead to xanthinuria, may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

(http://www.ncbi.nlm.nih.gov/gene/7498?ordinalpos=229&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum)

TXN

PharmTao.com — Thu, 26 Nov 2009 05:28:32 +0000

Gene:

TXN

Full Name:

thioredoxin [Homo sapiens]

Other Symbols:

RP11-427L11.1, DKFZp686B1993, MGC61975, TRX, TRX1

Chromosome Location:

9q31

OMIMID:

187700

GeneID:

7295

Sequences:

Nucleotide Protein

Human-Influenza Interactions:

Resistance of thioredoxin-transgenic mice against influenza virus-induced pneumonia was enhanced.

(http://www.ncbi.nlm.nih.gov/pubmed/12008049)

TNFSF4

PharmTao.com — Thu, 26 Nov 2009 05:26:18 +0000

Gene:

TNFSF4

Full Name:

tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens]

Other Symbols:

CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1

Other Names:

CD134 ligand; OX40 antigen ligand; tax-transcriptionally activated glycoprotein 1 (34kD)

Chromosome Location:

1q25

OMIMID:

603594

GeneID:

7292

Sequences:

Nucleotide Protein

Human-Influenza Interactions:

OX40L costimulates human antiviral memory CD8 T cell responses, enhances anti-influenza responses, especially in combination [...]