Gene:
Full Name:
tumor necrosis factor (TNF superfamily, member 2) [Homo sapiens]
Other Symbols:
DADB-70P7.1, DIF, TNF-alpha, TNFA, TNFSF2
Other Names:
APC1 protein; TNF superfamily, member 2; TNF, macrophage-derived; TNF, monocyte-derived; cachectin; tumor necrosis factor alpha
Chromosome Location:
6p21.3
OMIMID:
191160
GeneID:
7124
Sequences:
Human-Influenza Interactions:
- In elderly individuals, antibody titer to influenza A virus was lower, and the seroconversion factor was associated inversely with IL-10 production and associated directly with TNF-alpha production.
(http://www.ncbi.nlm.nih.gov/pubmed/16707559)
- In patients with influenza-associated encephalopathy, up-regulated to a greater extent than in those without neurologic complications.
(http://www.ncbi.nlm.nih.gov/pubmed/12934185)
- IFN-alpha and TNF-alpha are important in priming epithelial cells for higher cytokine and chemokine production in influenza A virus infection.
