Symbol:
Full Name:
interferon, alpha 1 [Homo sapiens]
Other Symbols:
IFL, IFN, IFN-ALPHA, IFNA13, IFNA@, MGC138207, MGC138505, MGC138507
Other Names:
IFN-alpha 1b; interferon alpha 1b
Chromosome Location:
9p22
OMIMID:
147660
GeneID:
3439
Sequences:
Family:
Interferon
Human-Influenza Interactions:
- In monocyte-derived dendritic cells, treatment of interferon alpha or toll-like receptor ligands protects against infection of avian influenza H5N1 virus.
(http://www.ncbi.nlm.nih.gov/pubmed/17911607)
- High levels of serum IFN-alpha are associated with febrile seizures in influenza.
(http://www.ncbi.nlm.nih.gov/pubmed/12435568)
- During influenza A virus infection, IFN-alpha and TNF-alpha are important for priming epithelial cells for higher cytokine and chemokine production.
(http://www.ncbi.nlm.nih.gov/pubmed/16253303)
- In influenza A virus-infected epithelial cells, RIG-I and mda-5 are positively regulated by IFN-alpha, and trigger antiviral cytokine gene expression.
