Herb-Drug Internations (21)

Tamarind (Tamarindus indica) – Aspirin

Interaction effect:
Increased bioavailability of aspirin

Reference:
A Mustapha, IA Yakasai and IA Aguye, Effect of Tamarindus indica L on the bioavailability of aspirin in healthy human volunteers, Eur Drug Metab Pharmacokinet 21 (1996), pp. 223–226.

Turmeric – Warfarin

Interaction effect:
Potential increase in risk of bleeding

Reference:
Heck AM, DeWitt BA, Lukes AL. [...]

Herb-Drug Interactions (20)

Saiboku-to (Asian herbal mixture) – Prednisolone

Interaction effect:
Increased prednisolone AUC

AUC = area under the concentration/time curve

Reference:
M Homma, K Oka and K Ikeshima et al., Different effects of traditional Chinese medicines containing similar herbal constituents on prednisolone pharmacokinetics, J Pharm Pharmacol 47 (1995), pp. 687–692.

Shankhapushpi (Ayurvedic mixed-herb syrup) – Phenytoin

Interaction effect:
Decreased phenytoin concentrations, loss [...]

Herb-Drug Interactions (19)

Flavonol glycosides (including hyperoside) – MAO-A

Interaction effect:
Inhibition

Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. St John’s wort (Hypericum perforatum): drug interactions and clinical outcomes. British Journal of Clinical Pharmacology 54 (4), 349-356.

Biflavones – Benzodiazepine receptor

Interaction effect:
Weak affinity

Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. [...]