Flavonol glycosides (including hyperoside) – MAO-A
Interaction effect:
Inhibition
Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. St John’s wort (Hypericum perforatum): drug interactions and clinical outcomes. British Journal of Clinical Pharmacology 54 (4), 349-356.
Biflavones – Benzodiazepine receptor
Interaction effect:
Weak affinity
Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. St John’s wort (Hypericum perforatum): drug interactions and clinical outcomes. British Journal of Clinical Pharmacology 54 (4), 349-356.
Xanthones – MAO-A
Interaction effect:
Inhibition
Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. St John’s wort (Hypericum perforatum): drug interactions and clinical outcomes. British Journal of Clinical Pharmacology 54 (4), 349-356.
Phloroglucinols (hyperforin) – GABA receptors
Interaction effect:
Affinity
Reference:
Henderson, L., Yue, Q. Y., Bergquist, C., Gerden, B. & Arlett, P. St John’s wort (Hypericum perforatum): drug interactions and clinical outcomes. British Journal of Clinical Pharmacology 54 (4), 349-356.
