Herb-Drug Interactions (8)

Ginseng (Panax spp) – Alcohol

Interaction effect:
Increased alcohol clearance

Reference:
FC Lee, JH Ko, JK Park and JS Lee, Effects of Panax ginseng on blood alcohol clearance in man, Clin Exp Pharmacol Physiol 14 (1987), pp. 543–546.

Green tea (Camelliasinensis) – Warfarin

Interaction effect:
Possible decrease in warfarin’s effects

Reference:
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. 2000 Jul 1;57(13):1221-7.

Guar gum (Cyamopsis tetragonolobus) – Metformin, phenoxymethylpenicillin, glibenclamide

Interaction effect:
Slows absorption of digoxin, paracetamol, and bumetanide; decreases absorption of metformin, phenoxymethylpenicillin, and some formulations of glibenclamide

Reference:
PAGM De Smet and PF D’Arcy, Drug interactions with herbal and other non-toxic remedies. In: PF D’Arcy, JC McElnay and PG Welling, Editors, Mechanisms of drug interactions, Springer-Verlag, Berlin (1996).

Horse chestnut – Warfarin

Interaction effect:
Potential increase in risk of bleeding

Reference:
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. 2000 Jul 1;57(13):1221-7.

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