Herb-Drug Interactions (9)

Kava (Piper methysticum) – Levodopa; (Benserazide)

Interaction effect:
Increased number and duration of ‘off’ periods

Reference:
Schelosky L, Raffauf C, Jendroska K, Poewe W. Kava and dopamine antagonism. J Neurol Neurosurg Psych 1995; 58: 639-640.

Kava (Piper methysticum) – Alprazolam; (Cimetidine, terazosin)

Interaction effect:
Lethargy, disorientation for several hours

Suggestions:
Probably no interaction but additive effects

Reference:
Almeida JC & Grimsley [...]

Herb-Drug Interactions (8)

Ginseng (Panax spp) – Alcohol

Interaction effect:
Increased alcohol clearance

Reference:
FC Lee, JH Ko, JK Park and JS Lee, Effects of Panax ginseng on blood alcohol clearance in man, Clin Exp Pharmacol Physiol 14 (1987), pp. 543–546.

Green tea (Camelliasinensis) – Warfarin

Interaction effect:
Possible decrease in warfarin’s effects

Reference:
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative [...]

Herb-Drug Interactions (7)

Ginkgo (Ginkgo biloba) – Thiazide diuretic

Interaction effect:
Hypertension

Reference:
PAGM De Smet and PF D’Arcy, Drug interactions with herbal and other non-toxic remedies. In: PF D’Arcy, JC McElnay and PG Welling, Editors, Mechanisms of drug interactions, Springer-Verlag, Berlin (1996).

Ginkgo (Ginkgo biloba) – Trazodone; (Bromazepam, donepezil, vitamin E discontinued within 3 days)

Interaction effect:
Coma; antiplatelet

Reference:
Galluzi S, [...]