Inflammation Database: genes: AGT (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))

AGT (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))

[ANHU, FLJ92595, FLJ97926, SERPINA8]

- Hyperglycemia may be related to the adverse renal effects of angiotensin II (AII). In the kidney, the glomerular mesangial cell is the main target of AII action. Glucose augments angiotensin II-induced proinflammatory gene expression in human mesangial cells (Naito et al., 2009). AII receptor [...]

Inflammation Database: genes involved in inflammation: AGER (advanced glycosylation end product-specific receptor)

AGER (advanced glycosylation end product-specific receptor)

[DAMA-358M23.4, MGC22357, RAGE]

- This gene belongs to the immunoglobulin superfamily of cell surface molecules (RefSeq, 2010). Higher oxidant stress and inflammation (OS/infl) have been associated with aging-related diseases and advanced glycation end products (AGEs). AGE receptor-1 (AGER1) is an antioxidant and can reduce OS/infl. Reduction of AGEs in normal diets has [...]

Hypertension: diagnosis, risk factors, and prevention

What is hypertension: symptoms, diagnosis, and risk factors

Only about half of people having hypertension are treated, and more than 30 percent of those who have hypertension do not know it. The force of blood against vessel walls is blood pressure. When the heart contracts, the blood pressure measured is called systolic pressure. When the heart is [...]