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SLC6A4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4) Other Symbols: 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, hSERT 1) Disease relevance: Bipolar disorder (BD) has been related to abnormal functions of the ventral anterior cingulate cortex (vACC) and the amygdale. Amygdale is involved in emotional regulation. Reduced functional connectivity from the vACC [...] SLC6A3 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 3) Other Symbols: DAT, DAT1 1) Disease relevance: The dopamine transporter gene (SLC6A3) may be a risk factor for pediatric bipolar disorder. The gene has been connected to attention deficit hyperactivity disorder (ADHD), and bipolar comorbidity with ADHD has been [...] SLC25A4 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4) Other Symbols: AAC1, ANT, ANT1, PEO2, PEO3, T1 Disease relevance: In several members of a family with bipolar psychiatric disorder, skeletal muscle biopsy from the proposita was found to have reduced cytochrome c oxidase staining and [...] |
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